SCHEMBL10476199

SCHEMBL10476199

O=C(NCCO)[C@@H](O)CO

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.65
ALDH1A1 P00352 2/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
MAPT P10636 1/20 0.65
OR51E2 Q9H255 1/20 0.42
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.39
PTGS1 P23219 1/20 0.38
KCNH2 Q12809 1/20 0.38
ALDH1A2 O94788 1/20 0.34
ALDH2 P05091 1/20 0.34
ALDH1A3 P47895 1/20 0.34
CNR1 P21554 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1399147 0.81 USP2 (0.60) USP2ALDH1A1MEN1KMT2AMAPT
SCHEMBL8895646 0.79 ALDH1A1 (0.58) USP2ALDH1A1MEN1KMT2AMAPT
SCHEMBL14602775 0.79 USP2 (1.00) USP2ALDH1A1MEN1KMT2AMAPT
SCHEMBL3871043 0.79 USP2 (1.00) USP2ALDH1A1MEN1KMT2AMAPT
SCHEMBL6732293 0.79 ALDH1A1 (0.64) USP2ALDH1A1MEN1KMT2AMAPT
SCHEMBL8895535 0.79 USP2 (1.00) USP2ALDH1A1MEN1KMT2AMAPT
SCHEMBL20090834 0.78 USP2 (0.56) USP2ALDH1A1MEN1KMT2AMAPT
SCHEMBL18783177 0.78 ALDH1A1 (0.56) USP2ALDH1A1MEN1KMT2AMAPT
SCHEMBL525215 0.77 ALDH1A1 (0.61) USP2ALDH1A1MEN1KMT2AMAPT
SCHEMBL4255667 0.76 USP2 (0.74) USP2ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120258061-A1 Method for Treating Skin with Retinoids and Retinoid Boosters CONOPCO, INC., D/B/A UNILEVER (US) 2012-10-11 US disclosed
US-8226933-B2 Method for treating skin with booster compositions UNILEVER HOME & PERSONAL CARE, USA DIVISION OF CONOPCO, INC. (US) 2012-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120258061-A1 Method for Treating Skin with Retinoids and Retinoid Boosters RARA, RARG, RARB USP2 2070/4885ALDH1A1 412/4885MEN1 4792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.