Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525215 | 0.81 | ALDH1A1 (0.61) | ALDH1A1USP2MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9247132 | 0.79 | ALDH1A1 (0.58) | ALDH1A1USP2MEN1KMT2AMAPT | |
| SCHEMBL10476199 | 0.79 | USP2 (0.65) | ALDH1A1USP2MEN1KMT2AMAPT | |
| SCHEMBL14602775 | 0.78 | USP2 (1.00) | ALDH1A1USP2MEN1KMT2AMAPT | |
| SCHEMBL8895535 | 0.78 | USP2 (1.00) | ALDH1A1USP2MEN1KMT2AMAPT | |
| SCHEMBL3871043 | 0.78 | USP2 (1.00) | ALDH1A1USP2MEN1KMT2AMAPT | |
| SCHEMBL16798146 | 0.77 | ALDH1A1 (0.56) | ALDH1A1USP2MEN1KMT2AMAPT | |
| SCHEMBL12143787 | 0.77 | USP2 (0.56) | ALDH1A1USP2MEN1KMT2AMAPT | |
| SCHEMBL4293765 | 0.76 | — | — | |
| SCHEMBL146290 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040076949-A1 | Methods for identifying inhibitors of helicase activity from hepatitis C virus | COLLETT MARC S (US) | 2004-04-22 | — | — | US | disclosed |
| US-20020081574-A1 | Methods for identifying inhibitors of helicase C virus | COLLETT MARC S (US) | 2002-06-27 | — | — | US | disclosed |
| US-5300439-A | Hydrophobic ionophore and reporter substance, hydrophilic polymer | MILES INC. (US) | 1994-04-05 | — | — | US | disclosed |