Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 11/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5185595 | 0.80 | PTGES (0.60) | PTGESSMN1; SMN2KMT2A | |
| SCHEMBL5257722 | 0.79 | SMN1; SMN2 (0.51) | NPC1SMN1; SMN2KMT2ARAB9ACASP3 | |
| SCHEMBL5255298 | 0.74 | PKM (0.58) | NPC1SMN1; SMN2KMT2ARAB9ACASP3 | |
| SCHEMBL4143003 | 0.74 | HPGD (0.69) | PTGESNPC1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL13872399 | 0.72 | NPC1 (0.62) | PTGESNPC1HPGDMAPK1 | |
| SCHEMBL5253493 | 0.71 | SMN1; SMN2 (0.45) | NPC1SMN1; SMN2KMT2ARAB9ACASP3 | |
| SCHEMBL5254786 | 0.70 | SMN1; SMN2 (0.44) | NPC1SMN1; SMN2HPGDKMT2ARAB9A | |
| SCHEMBL5187917 | 0.69 | SMN1; SMN2 (0.46) | NPC1SMN1; SMN2HPGDKMT2ARAB9A | |
| SCHEMBL21220006 | 0.68 | NPC1 (0.57) | PTGESNPC1HPGD | |
| SCHEMBL5257194 | 0.67 | PKM (0.43) | NPC1SMN1; SMN2KMT2ARAB9ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |
| EP-1399444-A2 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002100860-A2 | HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-12-19 | — | — | WO | disclosed |