Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557736 | 0.83 | ELANE (0.39) | — | |
| SCHEMBL20557593 | 0.72 | NPC1 (0.33) | HTR2AHTR2C | |
| SCHEMBL3300139 | 0.71 | — | — | |
| SCHEMBL20557398 | 0.71 | ELANE (0.38) | — | |
| SCHEMBL5258807 | 0.67 | PLK1 (0.50) | PLK1CSNK2A1PLK3HTR2AHTR2C | |
| SCHEMBL5252852 | 0.67 | ACE (0.43) | — | |
| SCHEMBL28923061 | 0.67 | PDK2 (0.35) | — | |
| SCHEMBL4696279 | 0.65 | AGTR2 (0.35) | — | |
| SCHEMBL26122592 | 0.64 | — | — | |
| SCHEMBL19064715 | 0.63 | MAP1LC3B (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798231-A2 | Intermediate products for the preparation of antibacterial compounds | NOVEXEL (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1399444-B1 | NOVEL HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | NOVEXEL (FR) | 2007-04-11 | — | — | EP | disclosed |