Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK2 | P53671 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR5A | P47898 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15071548 | 0.89 | HPGD (0.59) | LIMK2KMT2AMEN1OPRD1L3MBTL1 | |
| SCHEMBL6391784 | 0.87 | MEN1 (0.60) | LIMK2KMT2AMEN1OPRD1LMNA | |
| Bromide SCHEMBL28493092 | 0.87 | SIGMAR1 (0.56) | LIMK2KMT2AMEN1OPRD1L3MBTL1 | |
| SCHEMBL1926269 | 0.84 | HDAC1 (0.73) | KMT2AMEN1L3MBTL1HDAC1HDAC6 | |
| SCHEMBL9324870 | 0.84 | MEN1 (0.57) | LIMK2KMT2AMEN1OPRD1LMNA | |
| SCHEMBL1004019 | 0.84 | HDAC1 (0.71) | LIMK2KMT2AMEN1OPRD1L3MBTL1 | |
| SCHEMBL1003508 | 0.83 | HDAC1 (0.71) | KMT2AMEN1L3MBTL1HDAC1HDAC6 | |
| SCHEMBL8615545 | 0.82 | LIMK2 (0.63) | LIMK2KMT2AMEN1L3MBTL1HDAC1 | |
| SCHEMBL15111089 | 0.82 | RCE1 (0.68) | LIMK2KMT2AMEN1L3MBTL1HDAC1 | |
| SCHEMBL28884103 | 0.81 | HDAC1 (0.74) | LIMK2HDAC1HDAC6HDAC3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598111-B1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | UNILEVER PLC (GB) | 2015-03-25 | — | — | EP | disclosed |
| EP-2598111-B1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | UNILEVER PLC (GB) | 2015-03-25 | — | — | EP | disclosed |
| US-8476251-B2 | Skin care compositions comprising substituted diamines | CONOPCO, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476251-B2 | Skin care compositions comprising substituted diamines | CONOPCO, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476251-B2 | Skin care compositions comprising substituted diamines | CONOPCO, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| EP-2598111-A2 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | Unilever PLC (GB) | 2013-06-05 | — | — | EP | disclosed |
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2012013417-A2 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | UNILEVER PLC (GB) | 2012-02-02 | — | — | WO | disclosed |
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027700-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES | CUTA, TYR, DSG1 | LIMK2 3518/4885KMT2A 1051/4885MEN1 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.