SCHEMBL525469

SCHEMBL525469

NCCNC(C(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GGT1 P19440 1/20 0.48
GABRR1 P24046 2/20 0.42
CPB2 Q96IY4 7/20 0.35
GSR P00390 1/20 0.34
RNPEP Q9H4A4 1/20 0.33
CTH P32929 1/20 0.33
CPB1 P15086 1/20 0.33
LMNA P02545 1/20 0.32
GLRA1 P23415 1/20 0.32
SLC6A9 P48067 1/20 0.32
OR51E2 Q9H255 1/20 0.32
MEN1 O00255 1/20 0.32
CA12 O43570 1/20 0.32
CA6 P23280 1/20 0.32
CA7 P43166 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2153086 0.97 GGT1 (0.47) GGT1GABRR1CPB2GSRRNPEP
SCHEMBL29797936 0.97 GGT1 (0.47) GGT1GABRR1CPB2GSRRNPEP
SCHEMBL28085930 0.97 GGT1 (0.47) GGT1GABRR1CPB2GSRRNPEP
SCHEMBL29797573 0.97 GGT1 (0.47) GGT1GABRR1CPB2GSRRNPEP
SCHEMBL29223220 0.86 CA12 (0.48) GGT1GABRR1GSRRNPEPLMNA
SCHEMBL29516655 0.84 GGT1 (0.42) GGT1GABRR1CPB2CPB1
SCHEMBL1007236 0.83 LDHA (0.33) GGT1LMNAOR51E2RECQL
SCHEMBL10545490 0.81 PAOX (0.47) CPB2GSRRNPEPLMNAMEN1
SCHEMBL10356256 0.79 GGT1 (0.39) GGT1GABRR1LMNAMEN1CA12
SCHEMBL6342528 0.78 LDHA (0.30) GGT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626941-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE Dow Toray Co., Ltd. (JP) 2025-10-08 EP disclosed
CN-118255914-A Copolymer having carbosiloxane dendrimer structure, and composition, cosmetic raw material, film-forming agent and cosmetic containing the copolymer 陶氏东丽株式会社 2024-06-28 CN disclosed
WO-2024113195-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO., LTD. (JP) 2024-06-06 WO disclosed
CN-115052932-A Composition, method for preparing copolymer and end use of copolymer 美国陶氏有机硅公司 2022-09-13 CN disclosed
US-20210386651-A1 METHOD OF DESIGNING FILM-FORMING AGENT OR COSMETIC CONTAINING THE SAME DOW TORAY CO LTD (JP) 2021-12-16 US disclosed
US-20200222300-A1 FILM-FORMING AGENT FOR COSMETICS AND COSMETICS CONTAINING SAME DOW TORAY CO., LTD. (JP) 2020-07-16 US disclosed
EP-3646850-A1 FILM-FORMING AGENT FOR COSMETICS AND COSMETICS CONTAINING SAME Dow Toray Co., Ltd. (JP) 2020-05-06 EP disclosed
CN-109069368-A HYDROPHILIC SILANES 美国陶氏有机硅公司 2018-12-21 CN disclosed
EP-2658899-B1 COSMETIC CONTAINING LIQUID ORGANOPOLYSILOXANE DOW CORNING TORAY CO LTD (JP) 2018-08-01 EP disclosed
CN-108135827-A Film forming agent and the cosmetic combination and cosmetic preparation using the film forming agent 道康宁东丽株式会社 2018-06-08 CN disclosed
WO-2011136397-A1 NOVEL ORGANOPOLYSILOXANE, SURFACTANT, EMULSION COMPOSITION, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL, GELLING AGENT, GEL COMPOSITION, AND COSMETIC RAW MATERIAL COMPRISING NOVEL ORGANOPOLYSILOXANE, AS WELL AS, PREPARATION FOR EXTERNAL USE AND COSMETIC COMPRISING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011136389-A2 COSMETIC AND TOPICAL SKIN PREPARATION COMPRISING HIGHER ALCOHOL-MODIFIED SILICONE DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011081218-A1 PHENYL-CONTAINING ORGANOPOLYSILOXANE COMPOSITION, RAW COSMETIC MATERIAL, AND GLOSSY COSMETIC MATERIAL DOW CORNING TORAY CO., LTD. (JP) 2011-07-07 WO disclosed
WO-2011078407-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
WO-2011078395-A2 THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
WO-2011068250-A1 LINEAR AND CYCLIC SILOXANES AND COSMETIC COMPOSITIONS MADE THEREOF DOW CORNING TORAY CO., LTD. (JP) 2011-06-09 WO disclosed
WO-2011068251-A1 PRODUCTION METHOD OF DEODORIZED POLYOXYALKYLENE-MODIFIED POLYSILOXANE COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2011-06-09 WO disclosed
EP-1895979-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2008-03-12 EP disclosed
WO-2006137576-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2006-12-28 WO disclosed
US-4200238-A Method of preparing a rapidly soluble and machine handleable particulate composite and product OWENS-ILLINOIS, INC. (US) 1980-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200222300-A1 FILM-FORMING AGENT FOR COSMETICS AND COSMETICS CONTAINING SAME CUTA, WASHC5, WASHC4 GGT1 3991/4885GABRR1 1828/4885CPB2 4571/4885
US-20210386651-A1 METHOD OF DESIGNING FILM-FORMING AGENT OR COSMETIC CONTAINING THE SAME WASHC5, WASHC4, CUTA GGT1 3832/4885GABRR1 1200/4885CPB2 4553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.