Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.37 |
| ▸ | F2 | P00734 | 8/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225880 | 0.94 | P2RX7 (0.38) | P2RX7F2PRSS1ALDH1A1TP53 | |
| SCHEMBL5258334 | 0.86 | NAMPT (0.36) | P2RX7F2PRSS1ALDH1A1TP53 | |
| SCHEMBL5256634 | 0.83 | CYP1A2 (0.38) | P2RX7F2PRSS1SMN1; SMN2CYP3A4 | |
| SCHEMBL5259948 | 0.81 | P2RX7 (0.38) | P2RX7ALDH1A1SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL5256327 | 0.81 | P2RX7 (0.37) | P2RX7CYP3A4CYP2C9SCN5ASCN9A | |
| SCHEMBL5255111 | 0.79 | P2RX7 (0.34) | P2RX7ALDH1A1TP53SMN1; SMN2CYP3A4 | |
| SCHEMBL5257627 | 0.79 | CA12 (0.37) | P2RX7CYP3A4CYP2C9SCN5ASCN9A | |
| SCHEMBL5227174 | 0.78 | NAMPT (0.37) | P2RX7F2ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL5224364 | 0.76 | CYP1A2 (0.39) | P2RX7F2PRSS1SMN1; SMN2CYP3A4 | |
| SCHEMBL5227139 | 0.75 | ITGB1 (0.41) | P2RX7ALDH1A1SMN1; SMN2ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622867-B1 | N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS | ALMIRALL LAB (ES) | 2007-09-19 | — | — | EP | claimed |