Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5258338 | 0.85 | NAMPT (0.37) | NAMPTALDH1A1TP53SMN1; SMN2TRPV1 | |
| SCHEMBL5225880 | 0.82 | P2RX7 (0.38) | P2RX7ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL5256637 | 0.82 | CYP3A4 (0.37) | P2RX7FFAR1SMN1; SMN2TRPV1CYP3A4 | |
| SCHEMBL5259953 | 0.81 | FFAR1 (0.36) | P2RX7FFAR1ALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL5256333 | 0.80 | FFAR1 (0.37) | P2RX7FFAR1ALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL5255103 | 0.79 | P2RX7 (0.37) | P2RX7ALDH1A1TP53SMN1; SMN2TRPV1 | |
| SCHEMBL5257628 | 0.78 | CYP3A4 (0.36) | P2RX7FFAR1ALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL5182529 | 0.76 | LATS1 (0.40) | P2RX7FFAR1TRPV1 | |
| SCHEMBL5307756 | 0.70 | ITGA4 (0.44) | — | |
| SCHEMBL7107376 | 0.70 | ITGB1 (0.36) | FFAR1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622867-B1 | N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS | ALMIRALL LAB (ES) | 2007-09-19 | — | — | EP | claimed |