Nihydrazone

Nihydrazone

SCHEMBL525528

CC(=O)N/N=C/c1ccc([N+](=O)[O-])o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 1.00
TDP1 Q9NUW8 2/20 1.00
LMNA P02545 7/20 0.75
POLB P06746 4/20 0.75
ALDH1A1 P00352 6/20 0.74
CYP3A4 P08684 4/20 0.74
CYP1A2 P05177 4/20 0.74
KDM4E B2RXH2 4/20 0.74
SMN1; SMN2 Q16637 4/20 0.74
TP53 P04637 2/20 0.74
CYP2D6 P10635 2/20 0.74
HIF1A Q16665 1/20 0.74
PDE3A Q14432 1/20 0.74
SARM1 Q6SZW1 1/20 0.74
CYP2C19 P33261 2/20 0.68
CASP6 P55212 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
MAPT P10636 9/20 0.66
MITF O75030 4/20 0.66
MEN1 O00255 3/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nihydrazone SCHEMBL525529 1.00 HTT (1.00) HTTTDP1LMNAPOLBALDH1A1
Nitrofurazone SCHEMBL25417 0.85 LMNA (1.00) HTTTDP1LMNAPOLBALDH1A1
Nitrofurazone SCHEMBL25416 0.85 LMNA (1.00) HTTTDP1LMNAPOLBALDH1A1
Nitrofurazone SCHEMBL3681048 0.85 LMNA (1.00) HTTTDP1LMNAPOLBALDH1A1
Nitrofurazone SCHEMBL9928793 0.85 LMNA (0.87) HTTTDP1LMNAPOLBALDH1A1
Nitrofurazone SCHEMBL28198181 0.84 LMNA (0.97) HTTTDP1LMNAPOLBALDH1A1
Nitrofurazone SCHEMBL28285714 0.83 LMNA (0.94) HTTTDP1LMNAPOLBALDH1A1
Nifuraldezone SCHEMBL193102 0.83 LMNA (0.80) HTTTDP1LMNAPOLBALDH1A1
Nifuraldezone SCHEMBL193103 0.83 LMNA (0.80) HTTTDP1LMNAPOLBALDH1A1
SCHEMBL6549924 0.83 LMNA (0.71) HTTTDP1LMNAPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
EP-2788041-A1 ANTIFUNGAL CATHETER Rochester Medical Corporation (US) 2014-10-15 EP claimed
CN-104053460-A ANTIFUNGAL CATHETER ROCHESTER MEDICAL CORP 2014-09-17 CN claimed
US-20130150828-A1 ANTIFUNGAL CATHETER ROCHESTER MEDICAL CORPORATION (US) 2013-06-13 US claimed
WO-2013086195-A1 ANTIFUNGAL CATHETER ROCHESTER MEDICAL CORPORATION (US) 2013-06-13 WO claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
US-20080086214-A1 Medical device having a sleeve valve with bioactive agent WILSON-COOK MEDICAL INC. (US) 2008-04-10 US claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-0617631-B1 SUSTAINED-RELEASE BACTERICIDAL CANNULA ROCHESTER MEDICAL CORP (US) 1999-03-17 EP claimed
US-5482740-A Sustained release bactericidal cannula ROCHESTER MEDICAL CORPORATION (US) 1996-01-09 US claimed
EP-0617631-A4 SUSTAINED-RELEASE BACTERICIDAL CANNULA. ROCHESTER MEDICAL CORP (US) 1995-02-22 EP claimed
EP-0617631-A1 SUSTAINED-RELEASE BACTERICIDAL CANNULA ROCHESTER MEDICAL CORPORATION (US) 1994-10-05 EP claimed
US-5261896-A Sustained release bactericidal cannula ROCHESTER MEDICAL CORPORATION (US) 1993-11-16 US claimed
WO-1993011821-A1 SUSTAINED-RELEASE BACTERICIDAL CANNULA ROCHESTER MEDICAL CORPORATION (US) 1993-06-24 WO claimed
CN-119053238-A Memory cell with sidewall and bulk regions in vertical structures 美光科技公司 2024-11-29 CN disclosed
US-4044133-A FEED SUPPLEMENT, POULTRY, THIENO-PYRIDINE, OR FURO-PYRIDINE BASE N MERCK & CO., INC. (US) 1977-08-23 US disclosed
US-4006143-A COCCIDIOSTATS MERCK & CO., INC. (US) 1977-02-01 US disclosed