Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 16/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 5/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23146169 | 0.79 | — | — | |
| SCHEMBL19256888 | 0.75 | PTGS1 (0.38) | ACACBPTGS1ACACACYP2C9CYP2C19 | |
| SCHEMBL23146166 | 0.73 | LTA4H (0.35) | SLC6A3 | |
| SCHEMBL21029951 | 0.72 | NOS1 (0.41) | ACACBPTGS1ACACACYP2C9CYP2C19 | |
| SCHEMBL12701695 | 0.71 | PTGS1 (0.32) | ACACBPTGS1ACACACYP2C9 | |
| SCHEMBL6962358 | 0.71 | OGA (0.34) | HRH3OGA | |
| SCHEMBL25693140 | 0.71 | PIK3CD (0.34) | ACACBPTGS1ACACACYP2C9 | |
| SCHEMBL1368651 | 0.71 | PTGS1 (0.32) | ACACBPTGS1ACACACYP2C9 | |
| SCHEMBL26365157 | 0.71 | PTGS1 (0.32) | ACACBPTGS1ACACACYP2C9 | |
| SCHEMBL26049718 | 0.71 | MAPT (0.38) | SLC6A3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1960970-A | Pyrrolidine derivatives as CB1-receptor antagonists | TANABE SEIYAKU CO (JP) | 2007-05-09 | — | — | CN | disclosed |
| EP-1748980-A1 | PYRROLIDINE DERIVATIVES AS CB1-RECEPTOR ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005115977-A1 | PYRROLIDINE DERIVATIVES AS CB1-RECEPTOR ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 2005-12-08 | — | — | WO | disclosed |