Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 19/20 | 0.35 |
| ▸ | ACACA | Q13085 | 5/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257383 | 0.83 | ACACB (0.34) | ACACB | |
| SCHEMBL19256893 | 0.81 | GABRP (0.33) | ACACB | |
| SCHEMBL19257386 | 0.80 | LNPEP (0.33) | — | |
| SCHEMBL21029951 | 0.77 | NOS1 (0.41) | PTGS1ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL12701695 | 0.75 | PTGS1 (0.32) | PTGS1ACACBACACACYP2C9 | |
| SCHEMBL1368651 | 0.75 | PTGS1 (0.32) | PTGS1ACACBACACACYP2C9 | |
| SCHEMBL26365157 | 0.75 | PTGS1 (0.32) | PTGS1ACACBACACACYP2C9 | |
| SCHEMBL25693140 | 0.75 | PIK3CD (0.34) | PTGS1ACACBACACACYP2C9 | |
| SCHEMBL5255307 | 0.75 | HRH3 (0.34) | PTGS1ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL21772449 | 0.75 | PTGS1 (0.33) | PTGS1ACACBACACACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730449-B2 | Thiazole compound and its use in pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |