Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | PRKACG | P22612 | 1/20 | 0.31 |
| ▸ | PRKACB | P22694 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5259963 | 0.91 | ADRB3 (0.37) | TRPV1HDAC3HDAC1HDAC6ADRB3 | |
| SCHEMBL5255287 | 0.90 | HDAC3 (0.34) | TRPV1HDAC3HDAC1HDAC6ADRB3 | |
| SCHEMBL5255321 | 0.86 | JAK3 (0.37) | ADRB3 | |
| SCHEMBL5256333 | 0.84 | FFAR1 (0.37) | TRPV1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL5228649 | 0.81 | ITGB1 (0.37) | TRPV1HDAC3HDAC1HDAC6P2RX3 | |
| SCHEMBL5258338 | 0.79 | NAMPT (0.37) | TRPV1ADRB3 | |
| SCHEMBL5257897 | 0.78 | CA12 (0.36) | TRPV1HDAC3HDAC1HDAC6P2RX3 | |
| SCHEMBL5257628 | 0.75 | CYP3A4 (0.36) | TRPV1 | |
| SCHEMBL5261416 | 0.75 | TRPV1 (0.42) | TRPV1HDAC3HDAC1HDAC6PDE4B | |
| SCHEMBL5264743 | 0.75 | TRPV1 (0.42) | TRPV1HDAC3HDAC1HDAC6PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622867-B1 | N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS | ALMIRALL LAB (ES) | 2007-09-19 | — | — | EP | claimed |