Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255111 | 0.85 | P2RX7 (0.34) | NAMPTTRPV1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL5227174 | 0.83 | NAMPT (0.37) | NAMPTROCK2PRMT3ALDH1A1TP53 | |
| SCHEMBL5255321 | 0.82 | JAK3 (0.37) | NAMPTADRB3PRMT3SMN1; SMN2LCK | |
| SCHEMBL5259963 | 0.81 | ADRB3 (0.37) | ADRB3TRPV1 | |
| SCHEMBL5256231 | 0.79 | TRPV1 (0.34) | ADRB3TRPV1 | |
| SCHEMBL5258334 | 0.79 | NAMPT (0.36) | NAMPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL5255287 | 0.77 | HDAC3 (0.34) | NAMPTADRB3TRPV1 | |
| SCHEMBL5307756 | 0.75 | ITGA4 (0.44) | — | |
| SCHEMBL5264743 | 0.71 | TRPV1 (0.42) | TRPV1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5261416 | 0.71 | TRPV1 (0.42) | TRPV1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622867-B1 | N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS | ALMIRALL LAB (ES) | 2007-09-19 | — | — | EP | claimed |