Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5259953 | 0.91 | FFAR1 (0.36) | FFAR1SCN5ASCN9ACYP3A4CYP2C9 | |
| SCHEMBL5257628 | 0.91 | CYP3A4 (0.36) | FFAR1SCN5ASCN9ACYP3A4CYP2C9 | |
| SCHEMBL5256637 | 0.86 | CYP3A4 (0.37) | FFAR1SCN5ASCN9ACYP3A4CYP2C9 | |
| SCHEMBL5256231 | 0.84 | TRPV1 (0.34) | TRPV1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL5228936 | 0.80 | ITGB3 (0.39) | FFAR1SCN5ASCN9ACYP3A4CYP2C9 | |
| SCHEMBL5255111 | 0.80 | P2RX7 (0.34) | FFAR1SCN5ASCN9ACYP3A4CYP2C9 | |
| SCHEMBL5182529 | 0.80 | LATS1 (0.40) | FFAR1TRPV1GRM4DRD1P2RX7 | |
| SCHEMBL5256327 | 0.78 | P2RX7 (0.37) | FFAR1SCN5ASCN9ACYP3A4CYP2C9 | |
| SCHEMBL7107376 | 0.75 | ITGB1 (0.36) | FFAR1TRPV1GRM4DRD1 | |
| SCHEMBL5255287 | 0.75 | HDAC3 (0.34) | TRPV1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622867-B1 | N-(2-PHENYLETHYL)SULFAMIDE DERIVATIVES AS INTEGRIN ALPHA4 ANTAGONISTS | ALMIRALL LAB (ES) | 2007-09-19 | — | — | EP | claimed |