Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 4/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 5/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521447 | 0.87 | KIF11 (0.46) | ITKCNR2OPRM1KIF11EHMT2 | |
| SCHEMBL4392215 | 0.85 | PYGM (0.40) | ITKPYGMCNR2OPRM1KIF11 | |
| SCHEMBL11922696 | 0.79 | PYGM (0.43) | ITKPYGMCNR2KIF11CYP2C9 | |
| SCHEMBL4518845 | 0.76 | MC4R (0.61) | CNR2OPRM1 | |
| SCHEMBL4402052 | 0.72 | EHMT2 (0.44) | ITKCNR2OPRM1KIF11EHMT2 | |
| SCHEMBL4395041 | 0.72 | EHMT2 (0.47) | ITKCNR2OPRM1KIF11EHMT2 | |
| SCHEMBL5256358 | 0.72 | MC4R (0.44) | CNR2OPRM1NPC1ALDH1A1 | |
| SCHEMBL4395051 | 0.64 | CNR2 (0.56) | CNR2OPRM1EHMT2 | |
| SCHEMBL4396730 | 0.64 | MC4R (0.61) | CNR2OPRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4399463 | 0.64 | CNR2 (0.56) | CNR2OPRM1EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467974-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS GNRH ANTAGONISTS | SOD CONSEILS RECH APPLIC (FR) | 2007-08-15 | — | — | EP | disclosed |