Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prulifloxacin SCHEMBL13896543 | 0.89 | LMNA (1.00) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Prulifloxacin SCHEMBL1699755 | 0.89 | LMNA (1.00) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Prulifloxacin SCHEMBL7060281 | 0.89 | LMNA (1.00) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Prulifloxacin SCHEMBL29540773 | 0.89 | LMNA (1.00) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Prulifloxacin SCHEMBL136641 | 0.89 | LMNA (1.00) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Prulifloxacin SCHEMBL1650794 | 0.89 | LMNA (1.00) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Prulifloxacin SCHEMBL13822719 | 0.88 | LMNA (0.98) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Prulifloxacin SCHEMBL28660626 | 0.88 | LMNA (0.98) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Prulifloxacin SCHEMBL1231520 | 0.88 | LMNA (0.98) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Prulifloxacin SCHEMBL9673724 | 0.88 | LMNA (0.98) | LMNAALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626051-B1 | CRYSTALS OF QUINOLINECARBOXYLIC ACID DERIVATIVE SOLVATE | NIPPON SHINYAKU CO LTD (JP) | 2012-06-13 | — | — | EP | claimed |
| EP-1408034-B1 | Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents | SCHULZ & SCHLIMBACH GBR (DE) | 2007-08-08 | — | — | EP | claimed |
| EP-1408034-A1 | Use of Quinoline derivatives as antibacterial agents | Schulz & Schlimbach GbR (DE) | 2004-04-14 | — | — | EP | claimed |
| EP-1244434-A2 | USE OF CHEMOTHERAPEUTIC AGENTS | Schulz, Hans-Herrmann (DE) | 2002-10-02 | — | — | EP | claimed |
| WO-2001045679-A2 | USE OF CHEMOTHERAPEUTIC AGENTS FOR TOPICAL TREATMENT | SCHULZ HANS HERRMANN (DE) | 2001-06-28 | — | — | WO | claimed |
| EP-1408034-B1 | Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents | SCHULZ & SCHLIMBACH GBR (DE) | 2007-08-08 | — | — | EP | disclosed |
| EP-1408034-A1 | Use of Quinoline derivatives as antibacterial agents | Schulz & Schlimbach GbR (DE) | 2004-04-14 | — | — | EP | disclosed |