Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341823 | 0.78 | CTBP2 (0.39) | CTBP2TAAR1HPGDNPC1ALDH1A1 | |
| SCHEMBL23712598 | 0.77 | CTBP2 (0.47) | CTBP2TAAR1HPGDNPC1ALDH1A1 | |
| SCHEMBL641851 | 0.76 | PKM (0.50) | CTBP2TAAR1NPC1ALDH1A1KMT2A | |
| SCHEMBL9282256 | 0.76 | TAAR1 (0.42) | TAAR1NPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5780055 | 0.76 | LMNA (0.51) | TAAR1NPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5792021 | 0.75 | TAAR1 (0.48) | CTBP2TAAR1HPGDNPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL216730 | 0.73 | TAAR1 (0.47) | CTBP2TAAR1HPGDNPC1ALDH1A1 | |
| SCHEMBL7492800 | 0.72 | CTBP2 (0.50) | CTBP2TAAR1HPGDNPC1ALDH1A1 | |
| SCHEMBL1299233 | 0.71 | CTBP2 (0.55) | CTBP2TAAR1HPGDNPC1ALDH1A1 | |
| SCHEMBL8848834 | 0.71 | CTBP2 (0.46) | CTBP2TAAR1HPGDNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765795-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharmaceuticals SA (CH) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123703-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-12-29 | — | — | WO | disclosed |