SCHEMBL5260076

SCHEMBL5260076

Cc1ccc(C(=N)N)c(O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 5/20 0.55
PLG P00747 5/20 0.55
F10 P00742 4/20 0.55
PLAU P00749 4/20 0.55
PLAT P00750 3/20 0.55
TRPA1 O75762 2/20 0.50
ALOX15 P16050 2/20 0.45
HSD17B10 Q99714 2/20 0.45
ALDH1A1 P00352 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
TP53 P04637 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 2/20 0.42
CHRM1 P11229 1/20 0.42
SLC6A2 P23975 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
KLK1 P06870 2/20 0.41
KLK6 Q92876 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30755246 1.00 F2 (0.55) F2PLGF10PLAUPLAT
SCHEMBL8267256 0.83 PLAU (0.55) F2PLGF10PLAUPLAT
SCHEMBL2107802 0.80 PRSS1 (0.48) F2PLGF10PLAUPLAT
SCHEMBL22078964 0.80 TRPA1 (0.52) F2PLGF10PLAUPLAT
SCHEMBL14724818 0.78 NPC1 (0.53) F2PLGF10PLAUPLAT
SCHEMBL8212165 0.78 ALDH1A1 (0.50) F2PLGF10PLAUPLAT
SCHEMBL28839490 0.78 TRPA1 (0.50) F2PLGF10PLAUPLAT
SCHEMBL884070 0.78 NPC1 (0.53) F2PLGF10PLAUPLAT
SCHEMBL28022272 0.78 SELL (0.54) F2PLGF10PLAUPLAT
SCHEMBL28013376 0.77 CES2 (0.54) ALOX15HSD17B10ALDH1A1TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119855820-A Camptothecins compound and its preparation method and use 上海齐鲁制药研究中心有限公司 2025-04-18 CN disclosed
CN-114026077-A Novel oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2022-02-08 CN disclosed
CN-112996565-A Substituted 1,2, 4-oxadiazoles, their use and pharmaceutical preparations comprising them 斯文诺克斯制药有限责任公司 2021-06-18 CN disclosed
CN-110506040-A Kill the oxadiazole derivatives of microorganism SYNGENTA PARTICIPATIONS AG 2019-11-26 CN disclosed
CN-110461159-A Fungicidal compositions SYNGENTA PARTICIPATIONS AG 2019-11-15 CN disclosed
CN-109890209-A Kill the oxadiazole derivatives of microorganism 先正达参股股份有限公司 2019-06-14 CN disclosed
CN-109153657-A Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2019-01-04 CN disclosed
CN-109071522-A Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2018-12-21 CN disclosed
CN-109071520-A Kill the oxadiazole derivatives of microorganism 先正达参股股份有限公司 2018-12-21 CN disclosed
CN-108779109-A Kill microorganism oxadiazole derivatives 先正达参股股份有限公司 2018-11-09 CN disclosed
CN-108368098-A Kill microorganism oxadiazole derivatives 先正达参股股份有限公司 2018-08-03 CN disclosed
CN-108347936-A Kill microorganism oxadiazole derivatives 先正达参股股份有限公司 2018-07-31 CN disclosed
CN-108289448-A Kill microorganism oxadiazole derivatives 先正达参股股份有限公司 2018-07-17 CN disclosed
CN-108137570-A Kill microorganism oxadiazole derivatives 先正达参股股份有限公司 2018-06-08 CN disclosed
CN-108137517-A Kill microorganism oxadiazole derivatives 先正达参股股份有限公司 2018-06-08 CN disclosed
CN-107108638-A Piperidyl PyrazolopyrimidinonecGMP and application thereof 拜耳制药股份公司 2017-08-29 CN disclosed
WO-2012129564-A2 PROTEASOME CHYMOTRYPSIN-LIKE INHIBITION USING PI-1833 ANALOGS H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2012-09-27 WO disclosed
WO-2007076431-A1 MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-07-05 WO disclosed
EP-1765795-A2 ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS Addex Pharmaceuticals SA (CH) 2007-03-28 EP disclosed
WO-2005123703-A2 ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS ADDEX PHARMACEUTICALS SA (CH) 2005-12-29 WO disclosed