Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.44 |
| ▸ | CNR2 | P34972 | 12/20 | 0.44 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262358 | 0.88 | CNR1 (0.46) | CNR1CNR2FDFT1 | |
| SCHEMBL5260607 | 0.81 | TGFBR1 (0.34) | — | |
| SCHEMBL5260591 | 0.81 | CNR1 (0.48) | CNR1CNR2FDFT1 | |
| SCHEMBL5260356 | 0.78 | CNR1 (0.52) | CNR1CNR2FDFT1 | |
| SCHEMBL5263838 | 0.78 | CNR1 (0.50) | CNR1CNR2FDFT1 | |
| SCHEMBL5262390 | 0.76 | CNR1 (0.59) | CNR1CNR2FDFT1 | |
| SCHEMBL6325667 | 0.75 | CNR1 (0.45) | CNR1CNR2FDFT1 | |
| SCHEMBL5264060 | 0.74 | CNR1 (0.49) | CNR1CNR2FDFT1 | |
| SCHEMBL5262199 | 0.74 | CNR1 (0.49) | CNR1CNR2FDFT1 | |
| SCHEMBL5263940 | 0.74 | CNR1 (0.60) | CNR1CNR2FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494997-A4 | SUBSTITUTED ARYL AMIDES | MERCK & CO INC (US) | 2007-04-11 | — | — | EP | claimed |
| JP-2005527586-A | — | — | 2005-09-15 | — | — | JP | claimed |
| EP-1494997-A1 | SUBSTITUTED ARYL AMIDES | Merck & Co., Inc. (US) | 2005-01-12 | — | — | EP | claimed |
| WO-2003087037-A1 | SUBSTITUTED ARYL AMIDES | MERCK & CO., INC. (US) | 2003-10-23 | — | — | WO | claimed |
| EP-1494997-A4 | SUBSTITUTED ARYL AMIDES | MERCK & CO INC (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1494997-A1 | SUBSTITUTED ARYL AMIDES | Merck & Co., Inc. (US) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087037-A1 | SUBSTITUTED ARYL AMIDES | MERCK & CO., INC. (US) | 2003-10-23 | — | — | WO | disclosed |