Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896820 | 0.77 | CCR1 (0.46) | KDM4ENPC1BLMALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27638988 | 0.73 | DHODH (0.41) | KDM4ESCN5ASCN9A | |
| SCHEMBL9317262 | 0.73 | HSD11B1 (0.43) | MAP4K4ALOX15CDK1CDK2MKNK1 | |
| SCHEMBL30802290 | 0.72 | KDM4E (0.54) | KDM4ENPC1BLMMAP4K4ALOX15 | |
| SCHEMBL844746 | 0.72 | KDM4E (0.54) | KDM4ENPC1BLMMAP4K4ALOX15 | |
| SCHEMBL31555445 | 0.71 | SCN5A (0.49) | TGFBR1KDM4ENPC1BLMRXFP1 | |
| SCHEMBL15323277 | 0.71 | SCN5A (0.49) | TGFBR1KDM4ENPC1BLMRXFP1 | |
| SCHEMBL4905177 | 0.70 | ULK1 (0.47) | KDM4ENPC1SCN5ASCN9A | |
| SCHEMBL4166620 | 0.69 | TGFBR1 (0.56) | TGFBR1KDM4ENPC1BLMRXFP1 | |
| SCHEMBL30090604 | 0.69 | TGFBR1 (0.56) | TGFBR1KDM4ENPC1BLMRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737852-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | Icagen, Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100349-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | ICAGEN, INC. (US) | 2005-10-27 | — | — | WO | disclosed |