Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434577 | 0.85 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL56319 | 0.85 | LOX (0.57) | LMNAKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL12015821 | 0.84 | HTR6 (0.49) | KMT2AMEN1GAAALDH1A1MAPK1 | |
| SCHEMBL19152592 | 0.84 | MEN1 (0.49) | KMT2AMEN1GAAALDH1A1MAPK1 | |
| SCHEMBL19152146 | 0.84 | MEN1 (0.49) | LMNAKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL18390001 | 0.83 | MEN1 (0.69) | KMT2AMEN1ALDH1A1MAPK1POLB | |
| SCHEMBL5261643 | 0.83 | KMT2A (0.72) | KMT2AMEN1GAAALDH1A1LOX | |
| SCHEMBL7796947 | 0.82 | ALDH1A1 (0.49) | KMT2AMEN1GAAALDH1A1MAPK1 | |
| SCHEMBL20762267 | 0.81 | POLB (0.51) | LMNAKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL20982133 | 0.80 | MEN1 (0.49) | KMT2AMEN1GAAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888406-B1 | AZO COMPOUNDS | AVECIA LTD (GB) | 2001-12-12 | — | — | EP | disclosed |
| US-6008331-A | USEFUL AS BLACK COLORANTS FOR INK JET PRINTING INKS | ZENECA LIMITED (GB) | 1999-12-28 | — | — | US | disclosed |
| EP-0888406-A1 | AZO COMPOUNDS | ZENECA LIMITED (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032931-A1 | AZO COMPOUNDS | ZENECA LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |