Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228871 | 0.88 | MTNR1A (1.00) | MTNR1ATP53LMNAPOLBMTNR1B | |
| SCHEMBL7822666 | 0.87 | MTNR1A (0.77) | MTNR1ATP53LMNAPOLBMTNR1B | |
| SCHEMBL5227633 | 0.86 | MTNR1A (0.76) | MTNR1ATP53LMNAMTNR1B | |
| SCHEMBL5229036 | 0.85 | MTNR1A (0.74) | MTNR1ATP53LMNAPOLB | |
| SCHEMBL7027043 | 0.84 | MTNR1A (0.72) | MTNR1ATP53LMNA | |
| SCHEMBL5344278 | 0.84 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL5228827 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL5334595 | 0.82 | MTNR1A (0.70) | MTNR1ATP53MTNR1B | |
| SCHEMBL5346519 | 0.82 | MTNR1A (0.70) | MTNR1ALMNAPOLBMTNR1B | |
| SCHEMBL6076652 | 0.82 | MTNR1A (0.70) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998471-B1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-03-14 | — | — | EP | disclosed |
| US-6602903-B2 | Substituted O- and/or S heterocyclic compounds; powerful ligands for melatoninergic receptors. | LES LABORATORIES SERVIER (FR) | 2003-08-05 | — | — | US | disclosed |
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6313160-B1 | FOR THERAPY AND PROPHYLAXIS OF MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-11-06 | — | — | US | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |