Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.77 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261920 | 0.87 | MTNR1A (1.00) | MTNR1ATP53LMNAMTNR1BPOLB | |
| SCHEMBL5346165 | 0.82 | MTNR1A (0.70) | MTNR1AALOX5TP53TRPV1ITGB3 | |
| SCHEMBL7027043 | 0.81 | MTNR1A (0.72) | MTNR1AALOX5TP53TRPV1LMNA | |
| SCHEMBL5344278 | 0.81 | MTNR1A (0.72) | MTNR1AALOX5TRPV1ITGB3ITGA2B | |
| SCHEMBL6076652 | 0.80 | MTNR1A (0.70) | MTNR1AALOX5TRPV1ITGB3ITGA2B | |
| SCHEMBL5334595 | 0.80 | MTNR1A (0.70) | MTNR1AALOX5TP53TRPV1ITGB3 | |
| SCHEMBL5346519 | 0.80 | MTNR1A (0.70) | MTNR1ATRPV1LMNAMTNR1BPOLB | |
| SCHEMBL5336254 | 0.77 | MTNR1A (0.70) | MTNR1ATP53TRPV1ITGB3ITGA2B | |
| SCHEMBL19658437 | 0.76 | MTNR1A (0.65) | MTNR1ATP53MTNR1B | |
| SCHEMBL5228871 | 0.76 | MTNR1A (1.00) | MTNR1ATP53LMNAMTNR1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077928-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 2001-02-28 | — | — | EP | claimed |
| WO-1999058496-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-11-18 | — | — | WO | claimed |