Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261920 | 0.84 | MTNR1A (1.00) | MTNR1ATP53LMNA | |
| SCHEMBL7822666 | 0.81 | MTNR1A (0.77) | MTNR1AALOX5TP53TRPV1LMNA | |
| SCHEMBL5344278 | 0.78 | MTNR1A (0.72) | MTNR1AALOX5DRD3TRPV1 | |
| SCHEMBL5346165 | 0.77 | MTNR1A (0.70) | MTNR1AALOX5TP53TRPV1 | |
| SCHEMBL5346519 | 0.77 | MTNR1A (0.70) | MTNR1ATRPV1LMNA | |
| SCHEMBL5334595 | 0.77 | MTNR1A (0.70) | MTNR1AALOX5TP53TRPV1 | |
| SCHEMBL6076652 | 0.77 | MTNR1A (0.70) | MTNR1AALOX5TRPV1 | |
| SCHEMBL5336254 | 0.75 | MTNR1A (0.70) | MTNR1ATP53TRPV1RORC | |
| SCHEMBL19658437 | 0.74 | MTNR1A (0.65) | MTNR1ATP53 | |
| SCHEMBL5228871 | 0.73 | MTNR1A (1.00) | MTNR1ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |