Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 5/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 6/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5260483 | 0.79 | PIM1 (0.37) | FAAHNPC1RAB9A | |
| SCHEMBL5316067 | 0.77 | TRPC3 (0.40) | FAAHSPRTRPC3TRPC6RBP4 | |
| SCHEMBL16103438 | 0.60 | MAPK14 (0.49) | ALDH1A1HTTHSD17B10CCR5NPC1 | |
| SCHEMBL1045160 | 0.59 | HTR2C (0.44) | FAAHSPRTRPC3TRPC6ALDH1A1 | |
| SCHEMBL2188470 | 0.59 | KDM4E (0.51) | SPRALDH1A1 | |
| SCHEMBL5800122 | 0.58 | HCRTR1 (0.43) | FAAHALDH1A1TSHRHTR2C | |
| SCHEMBL5662280 | 0.58 | KDM4E (0.43) | ALDH1A1HSD17B10CCR5NPC1 | |
| SCHEMBL13419445 | 0.57 | FAAH (0.45) | FAAHALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL2186962 | 0.57 | LMNA (0.56) | ALDH1A1TSHRHTTNPSR1HSD17B10 | |
| SCHEMBL3676189 | 0.57 | CYP3A4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1834954-A1 | Thiazoles as NF-kB Inhibitors (proteasome inhibitors) | 4SC AG (DE) | 2007-09-19 | — | — | EP | disclosed |