Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16087778 | 0.87 | FOLH1 (0.45) | FOLH1TSHRKMT2ASLC1A1GABRP | |
| SCHEMBL28875506 | 0.84 | MGAM (0.41) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL712103 | 0.81 | GABRP (0.38) | FOLH1KMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL6870428 | 0.81 | CA2 (0.55) | TSHRKMT2AMGAMGAASI | |
| SCHEMBL14672410 | 0.80 | GABRP (0.45) | FOLH1KMT2AMEN1NPC1GABRP | |
| SCHEMBL6863987 | 0.79 | BIRC2 (0.49) | KMT2AMEN1SLC1A1MGAMGAA | |
| SCHEMBL712102 | 0.78 | L3MBTL1 (0.51) | TSHRKMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL6871632 | 0.78 | ZDHHC7 (0.49) | KMT2AMEN1POLBCPB2 | |
| SCHEMBL6868546 | 0.78 | ZDHHC7 (0.49) | KMT2AMEN1POLBCPB2 | |
| SCHEMBL6873375 | 0.78 | ZDHHC7 (0.49) | KMT2AMEN1POLBCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621545-A1 | APOPTOSIS IMAGING AGENTS BASED ON LANTIBIOTIC PEPTIDES | GE Healthcare UK Limited (GB) | 2013-08-07 | — | — | EP | disclosed |
| EP-2598175-A1 | RADIOPHARMACEUTICAL COMPOSITIONS | GE Healthcare Limited (GB) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012119937-A1 | TECHNETIUM LABELLED PEPTIDES | GE HEALTHCARE LIMITED (GB) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012041862-A1 | APOPTOSIS IMAGING AGENTS BASED ON LANTIBIOTIC PEPTIDES | GE HEALTHCARE LIMITED (GB) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012013701-A1 | RADIOPHARMACEUTICAL COMPOSITIONS | GE HEALTHCARE LIMITED (GB) | 2012-02-02 | — | — | WO | disclosed |
| EP-1991526-A1 | TETRACYCLIC INDOLE DERIVATIVES AS IN VIVO IMAGING AGENTS AND HAVING PERIPHERALBENZODIAZEPINE RECEPTOR AFFINITY (PBR) | Hammersmith Imanet, Ltd (GB) | 2008-11-19 | — | — | EP | disclosed |
| EP-1979004-A2 | CONJUGATES OF SEMAPHORIN PEPTIDES AS IMAGING AGENTS FOR CANCER | GE Healthcare Limited (GB) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007057705-A1 | TETRACYCLIC INDOLE DERIVATIVES AS IN VIVO IMAGING AGENTS AND HAVING PERIPHERALBENZODIAZEPINE RECEPTOR AFFINITY (PBR) | HAMMERSMITH IMANET LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007049061-A2 | CONJUGATES OF SEMAPHORIN PEPTIDES AS IMAGING AGENTS FOR CANCER | GE HEALTHCARE LIMITED (GB) | 2007-05-03 | — | — | WO | disclosed |
| EP-1682113-A1 | INHIBITOR IMAGING AGENTS | GE Healthcare Limited (GB) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005049005-A1 | INHIBITOR IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2005-06-02 | — | — | WO | disclosed |