Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720836 | 0.85 | ADORA2A (0.79) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL18760499 | 0.85 | MEN1 (0.57) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL3165362 | 0.85 | MEN1 (0.57) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL6038198 | 0.84 | ADORA2A (0.46) | ADORA2AADORA1ADORA2BKMT2AMEN1 | |
| SCHEMBL2118725 | 0.81 | MEN1 (0.59) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL1490059 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL3307656 | 0.79 | MEN1 (0.68) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL13933596 | 0.76 | ADORA2A (0.66) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL19417188 | 0.76 | ADORA2A (0.92) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL3156245 | 0.76 | ADORA2A (0.66) | ADORA2AADORA1ADORA3ADORA2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794135-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006037117-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2006-04-06 | — | — | WO | disclosed |
| US-20060069110-A1 | Substituted heterocyclic compounds and methods of use | AMGEN INC. | 2006-03-30 | — | — | US | disclosed |
| EP-0297397-B1 | PREPARATION OF DIAZO AND AZO COMPOUNDS | BAYER AG (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-4942225-A | Preparation of diazo and azo compounds using azidoformamidium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0218206-B1 | DISAZO PIGMENTS HAVING A PIPERAZINE BRIDGING MEMBER | BASF Aktiengesellschaft (DE) | 1990-02-07 | — | — | EP | disclosed |
| EP-0297397-A2 | Preparation of diazo and azo compounds | BAYER AG (DE) | 1989-01-04 | — | — | EP | disclosed |
| US-4764599-A | INK PIGMENTS, SURFACE COATING, PLASTICS-SULFUR-FREE | BASF AKTIENGESELLSCHAFT (DE) | 1988-08-16 | — | — | US | disclosed |
| EP-0120255-B1 | REACTIVE DYES | BAYER AG (DE) | 1987-04-15 | — | — | EP | disclosed |
| EP-0218206-A2 | Disazo pigments having a piperazine bridging member | BASF Aktiengesellschaft (DE) | 1987-04-15 | — | — | EP | disclosed |
| US-4556707-A | DYEING CELLULOSE FIBERS AND POLYAMIDE FIBERS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-03 | — | — | US | disclosed |
| EP-0073463-B1 | INSERTION COMPOUNDS, INTERCALATION COMPOUNDS AND SOLID SOLUTIONS OF COLOURED METALLIC ORGANIC DERIVATIVES | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| US-4540776-A | Reactive fluorotriazinylaminonaphthotriazolyphenylazopyridone or pyrimidone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| EP-0120255-A1 | Reactive dyes | BAYER AG (DE) | 1984-10-03 | — | — | EP | disclosed |
| EP-0093306-A1 | Methods for the preparation of azo compounds, and azo compounds | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |
| EP-0088930-A2 | Triazole-triazinyl azo dyes | BAYER AG (DE) | 1983-09-21 | — | — | EP | disclosed |
| US-4354968-A | Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component | BAYER AKTIENGESELLSCHAFT (DE) | 1982-10-19 | — | — | US | disclosed |
| EP-0013879-B1 | REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE FOR DYEING MATERIALS CONTAINING HYDROXYL OR AMIDE GROUPS | BAYER AG (DE) | 1982-09-15 | — | — | EP | disclosed |
| EP-0013879-A1 | Reactive dyestuffs, their preparation and their use for dyeing materials containing hydroxyl or amide groups | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069110-A1 | Substituted heterocyclic compounds and methods of use | MAPT, MYLK2, IAPP | ADORA2A 104/4885ADORA1 370/4885ADORA3 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.