Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18760499 | 1.00 | MEN1 (0.57) | MEN1KMT2ANTSR1ADORA1ADORA2A | |
| SCHEMBL2118725 | 0.95 | MEN1 (0.59) | MEN1KMT2ANTSR1ADORA1ADORA2A | |
| SCHEMBL3307656 | 0.89 | MEN1 (0.68) | MEN1KMT2ANTSR1ADORA1ADORA2A | |
| SCHEMBL2577307 | 0.85 | LMNA (0.61) | MEN1KMT2ANTSR1L3MBTL1MAPK1 | |
| SCHEMBL5262287 | 0.85 | ADORA2A (0.66) | MEN1KMT2ANTSR1ADORA1ADORA2A | |
| SCHEMBL10645121 | 0.85 | LMNA (0.61) | MEN1KMT2ANTSR1ADORA1ADORA2A | |
| SCHEMBL4803909 | 0.82 | KMT2A (0.59) | MEN1KMT2ANTSR1ADORA1ADORA2A | |
| SCHEMBL981519 | 0.82 | HPGDS (0.46) | MEN1KMT2ANTSR1ADORA1ADORA2A | |
| SCHEMBL602293 | 0.82 | LMNA (0.64) | MEN1KMT2ANTSR1POLBL3MBTL1 | |
| SCHEMBL9003232 | 0.80 | MEN1 (0.44) | MEN1KMT2ANTSR1ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677596-A | Preparation process of herbicidal safener fenclorim | 江苏莱科化学有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-110452355-B | Self-repairing rat-proof and termite-proof polyurethane, preparation method and application | 安徽建筑大学 | 2021-07-16 | — | — | CN | claimed |
| CN-101357904-A | 2-phenyl-4,6-dichloro pyrimidine preparation method | JIANGSU CHANGLONG CHEMICAL CO (CN) | 2009-02-04 | — | — | CN | claimed |
| EP-1796673-A2 | NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Reddy US Therapeutics, Inc. (US) | 2007-06-20 | — | — | EP | claimed |
| US-20060084645-A1 | Novel pyrimidine compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-20 | — | — | US | claimed |
| WO-2006034473-A2 | NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS, INC. (US) | 2006-03-30 | — | — | WO | claimed |
| EP-0738717-A1 | Certain substituted pyrimidines as intermediates for production of cycloalkyl and azacycloalkyl pyrrolopyrimidines | NEUROGEN CORPORATION (US) | 1996-10-23 | — | — | EP | claimed |
| EP-0055693-A1 | Use of phenyl pyrimidines as protecting agents for culture plants against phytotoxic damage caused by herbicides | CIBA-GEIGY AG (CH) | 1982-07-07 | — | — | EP | claimed |
| CN-222151961-U | Chloridizing system for grass-removing pyridine | 江苏莱科化学有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-222151961-U | Chloridizing system for grass-removing pyridine | 江苏莱科化学有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118525862-A | Gold nanoparticle and preparation method and application thereof | 佛山鲲鹏现代农业研究院 | 2024-08-23 | — | — | CN | disclosed |
| EP-2713736-B1 | NOVEL IMMUNE SYSTEM MODULATORS | JANUS BIOTHERAPEUTICS INC (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-2713736-B1 | NOVEL IMMUNE SYSTEM MODULATORS | JANUS BIOTHERAPEUTICS INC (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-115677596-A | Preparation process of herbicidal safener fenclorim | 江苏莱科化学有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-4354968-A | Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component | BAYER AKTIENGESELLSCHAFT (DE) | 1982-10-19 | — | — | US | disclosed |
| EP-0013879-B1 | REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE FOR DYEING MATERIALS CONTAINING HYDROXYL OR AMIDE GROUPS | BAYER AG (DE) | 1982-09-15 | — | — | EP | disclosed |
| EP-0055693-A1 | Use of phenyl pyrimidines as protecting agents for culture plants against phytotoxic damage caused by herbicides | CIBA-GEIGY AG (CH) | 1982-07-07 | — | — | EP | disclosed |
| US-4264494-A | Chromium complex dyestuffs for natural polyamides and synthetic nylons | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
| EP-0013879-A1 | Reactive dyestuffs, their preparation and their use for dyeing materials containing hydroxyl or amide groups | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084645-A1 | Novel pyrimidine compounds, process for their preparation and compositions containing them | UMPS, DPYD, TYMS | MEN1 4470/4885KMT2A 4623/4885NTSR1 3269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.