SCHEMBL526231

SCHEMBL526231

CCCCCCCCc1sc(-c2ccnc(-c3ccccc3)c2)c2c1OCCO2

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
SREBF2 Q12772 1/20 0.35
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HTR1A P08908 1/20 0.33
HTR7 P34969 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
STAT1 P42224 1/20 0.33
RAB9A P51151 1/20 0.33
PIM1 P11309 1/20 0.33
ASIC3 Q9UHC3 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL526039 0.84 AR (0.31)
SCHEMBL12958383 0.74 RAB9A (0.33) MAPTSMN1; SMN2NPC1ALDH1A1RAB9A
SCHEMBL526002 0.74 HSD17B1 (0.41) MAPTSREBF2TP53SMN1; SMN2NPC1
SCHEMBL526244 0.73 SREBF2 (0.42) MAPTSREBF2TP53SMN1; SMN2HTR1A
SCHEMBL526382 0.73 MAPT (0.40) MAPTSREBF2TP53SMN1; SMN2HTR1A
SCHEMBL526704 0.72 HSD17B1 (0.39) MAPTSREBF2TP53SMN1; SMN2NPC1
SCHEMBL12958400 0.72 KCNH2 (0.36)
SCHEMBL18775537 0.72
SCHEMBL18790476 0.70 HSD11B1 (0.52) MAPTSMN1; SMN2NPC1ALDH1A1RAB9A
SCHEMBL16731372 0.70 KDM4E (0.36) NPC1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012013719-A1 NEW CYCLOMETALATED COMPLEXES FOR SOLAR CELLS UNIVERSITA' DEGLI STUDI DI MILANO BICOCCA (IT) 2012-02-02 WO disclosed