Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15102612 | 1.00 | GLA (0.42) | GLACACNA1BAPBA1NPSR1TDP1 | |
| SCHEMBL13209207 | 0.79 | GAA (0.44) | GLACACNA1BAPBA1NPSR1TDP1 | |
| SCHEMBL2945465 | 0.79 | NOS1 (0.40) | TDP1KMT2AMEN1LMNATSHR | |
| SCHEMBL12116657 | 0.79 | GAA (0.44) | GLACACNA1BAPBA1NPSR1TDP1 | |
| SCHEMBL441773 | 0.79 | NOS1 (0.40) | TDP1KMT2AMEN1LMNATSHR | |
| SCHEMBL3773521 | 0.79 | GAA (0.44) | GLACACNA1BAPBA1NPSR1TDP1 | |
| SCHEMBL19490643 | 0.79 | KMT2A (0.49) | GLACACNA1BAPBA1NPSR1TDP1 | |
| SCHEMBL3081216 | 0.79 | KMT2A (0.49) | GLACACNA1BAPBA1NPSR1TDP1 | |
| SCHEMBL3081213 | 0.79 | KMT2A (0.49) | GLACACNA1BAPBA1NPSR1TDP1 | |
| SCHEMBL24100590 | 0.78 | OGG1 (0.41) | KMT2AMEN1LMNAMAPTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781662-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | Pfizer, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018725-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-02-23 | — | — | WO | disclosed |