Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945465 | 1.00 | NOS1 (0.40) | NOS1MEN1KMT2AMAOAMAOB | |
| SCHEMBL3960842 | 0.81 | GAA (0.43) | NOS1MEN1KMT2AMAOAMAOB | |
| SCHEMBL23118889 | 0.80 | TSHR (0.50) | TSHRCYP2C19F2SMN1; SMN2CES1 | |
| SCHEMBL15102612 | 0.79 | GLA (0.42) | MEN1KMT2ACYP3A4TDP1MAPT | |
| SCHEMBL20777964 | 0.79 | MASP2 (0.39) | MEN1KMT2ACYP3A4TDP1MAPT | |
| SCHEMBL5262398 | 0.79 | GLA (0.42) | MEN1KMT2ACYP3A4TDP1MAPT | |
| SCHEMBL20364008 | 0.78 | AKR1C3 (0.53) | MEN1KMT2AMAOBF2F10 | |
| SCHEMBL21339902 | 0.77 | OGG1 (0.52) | NOS1MAPTF2POLBRECQL | |
| SCHEMBL4959117 | 0.77 | NOS1 (0.57) | NOS1MEN1KMT2AMAOAMAOB | |
| SCHEMBL8443723 | 0.76 | MAOA (0.39) | MEN1KMT2AMAOAMAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576093-A4 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS INC (US) | 2009-07-08 | — | — | EP | claimed |
| US-20070065443-A1 | Fructoseamine 3 kinase and the formation of collagen and elastin | DYNAMIS THERAPEUTICS, INC. | 2007-03-22 | — | — | US | claimed |
| EP-1753861-A2 | FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN | Dynamis Therapeutics, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1576093-A2 | 3-DEOXYGLUCOSONE AND SKIN | Dynamis Therapeutics, Inc. (US) | 2005-09-21 | — | — | EP | claimed |
| WO-2005079463-A2 | FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN | DYNAMIS THERAPEUTICS, INC. (US) | 2005-09-01 | — | — | WO | claimed |
| US-20050159383-A1 | Administering enzyme inhibitors; wrinkling and aging resistance; prevents formation Advanced Glycation End Products (AGEs) | DYNAMIS THERAPEUTICS, INC. | 2005-07-21 | — | — | US | claimed |
| US-20030219440-A1 | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS, INC. | 2003-11-27 | — | — | US | claimed |
| WO-2003089601-A2 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS, INC. (US) | 2003-10-30 | — | — | WO | claimed |
| US-9758666-B2 | Oxygen-absorbing resin composition and oxygen-absorbing multilayer body using the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9725562-B2 | Modified diene polymer, method for producing same, rubber composition, and pneumatic tire | TOYO TIRE & RUBBER CO., LTD. (JP) | 2017-08-08 | — | — | US | disclosed |
| EP-2894194-B1 | OXYGEN-ABSORBING RESIN COMPOSITION AND OXYGEN-ABSORBING MULTILAYER BODY USING SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2017-01-11 | — | — | EP | disclosed |
| CN-104603195-B | Oxygen-absorbing resin composition and the oxygen uptake polylayer forest using it | 三菱瓦斯化学株式会社 | 2016-09-21 | — | — | CN | disclosed |
| US-20150353690-A1 | MODIFIED DIENE POLYMER, METHOD FOR PRODUCING SAME, RUBBER COMPOSITION, AND PNEUMATIC TIRE | TOYO TIRE & RUBBER CO., LTD. (JP) | 2015-12-10 | — | — | US | disclosed |
| US-20150203678-A1 | OXYGEN-ABSORBING RESIN COMPOSITION AND OXYGEN-ABSORBING MULTILAYER BODY USING THE SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2015-07-23 | — | — | US | disclosed |
| EP-1175155-A1 | METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF | FOX CHASE CANCER CENTER (US) | 2002-01-30 | — | — | EP | disclosed |
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |
| WO-2000062626-A1 | METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF | FOX CHASE CANCER CENTER (US) | 2000-10-26 | — | — | WO | disclosed |
| WO-1999024395-A1 | COMPOUNDS WHICH INHIBIT TRYPTASE ACTIVITY | ARRAY BIOPHARMA, INC. (US) | 1999-05-20 | — | — | WO | disclosed |
| US-5262152-A | Aging resistance, inhibiting glycosylation of proteins | THE ROCKEFELLER UNIVERSITY (US) | 1993-11-16 | — | — | US | disclosed |
| US-5130337-A | Aging of proteins by reaction with glucose or other reducing sugar | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070065443-A1 | Fructoseamine 3 kinase and the formation of collagen and elastin | FN3K, PDXK, COLGALT1 | NOS1 2488/4885MEN1 1069/4885KMT2A 2468/4885 |
| US-20030219440-A1 | 3-deoxyglucosone and skin | DPM1, G6PD, UGGT1 | NOS1 2487/4885MEN1 1559/4885KMT2A 3495/4885 |
| US-20050159383-A1 | Administering enzyme inhibitors; wrinkling and aging resistance; prevents formation Advanced Glycation End Products (AGEs) | AGER, GLA, GALE | NOS1 515/4885MEN1 3627/4885KMT2A 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.