Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262396 | 1.00 | RAB9A (0.47) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| SCHEMBL23188035 | 1.00 | RAB9A (0.47) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| SCHEMBL30605712 | 0.82 | L3MBTL1 (0.50) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| SCHEMBL101690 | 0.82 | L3MBTL1 (0.50) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| SCHEMBL20099346 | 0.82 | RAB9A (0.47) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| SCHEMBL101689 | 0.82 | L3MBTL1 (0.50) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| SCHEMBL12997622 | 0.82 | L3MBTL1 (0.50) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| SCHEMBL28296397 | 0.81 | CYP2D6 (0.56) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11770197 | 0.79 | CYP2D6 (0.55) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11770190 | 0.79 | CYP2D6 (0.55) | RAB9ANPC1POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781662-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | Pfizer, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018725-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-02-23 | — | — | WO | disclosed |