SCHEMBL101690

SCHEMBL101690

Cc1ccccc1C(N)=NO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.50
GAA P10253 4/20 0.50
LMNA P02545 3/20 0.50
RAB9A P51151 5/20 0.47
NPC1 O15118 4/20 0.47
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 2/20 0.45
PKM P14618 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MAPT P10636 2/20 0.42
HPGD P15428 2/20 0.42
ALOX12 P18054 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HTT P42858 2/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
TSHR P16473 1/20 0.39
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101689 1.00 L3MBTL1 (0.50) L3MBTL1GAALMNARAB9ANPC1
SCHEMBL30605712 1.00 L3MBTL1 (0.50) L3MBTL1GAALMNARAB9ANPC1
SCHEMBL12997622 1.00 L3MBTL1 (0.50) L3MBTL1GAALMNARAB9ANPC1
SCHEMBL102965 0.83 LMNA (0.43) L3MBTL1GAALMNARAB9ANPC1
SCHEMBL102966 0.83 LMNA (0.43) L3MBTL1GAALMNARAB9ANPC1
SCHEMBL23188035 0.82 RAB9A (0.47) L3MBTL1GAALMNARAB9ANPC1
SCHEMBL20099346 0.82 RAB9A (0.47) L3MBTL1GAALMNARAB9ANPC1
SCHEMBL5262402 0.82 RAB9A (0.47) L3MBTL1GAALMNARAB9ANPC1
SCHEMBL5262396 0.82 RAB9A (0.47) L3MBTL1GAALMNARAB9ANPC1
SCHEMBL21163486 0.79 GAA (0.41) L3MBTL1GAALMNARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11424006-B2 Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide PSOMAGEN, INC. (US) 2022-08-23 US claimed
US-20210128498-A1 TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE MACROGEN INC. (KR) 2021-05-06 US claimed
EP-3668494-A1 TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE Psomagen, Inc. (US) 2020-06-24 EP claimed
WO-2019036507-A1 TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE uBiome, Inc. (US) 2019-02-21 WO claimed
US-20190050525-A1 RIESKE-TYPE OXYGENASE/REDUCTASE TARGETED DRUGS FOR DIAGNOSTIC AND TREATMENT OF DISEASES PSOMAGEN, INC. 2019-02-14 US claimed
US-20140026782-A1 SILVER INK COMPOSITION INKTEC CO., LTD. (KR) 2014-01-30 US claimed
US-8486203-B2 Conversion coating and anodizing sealer with no chromium METALAST INTERNATIONAL, INC. (US) 2013-07-16 US claimed
WO-2012144847-A2 SILVER INK COMPOSITION 주식회사 잉크테크 (KR) 2012-10-26 WO claimed
US-20100314004-A1 CONVERSION COATING AND ANODIZING SEALER WITH NO CHROMIUM CHEMEON SURFACE TECHNOLOGY, LLC 2010-12-16 US claimed
US-20070114155-A1 Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof TOTAL RAFFINAGE FRANCE (FR) 2007-05-24 US claimed
JP-2007501701-A 2007-02-01 JP claimed
EP-1660232-A1 HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF Total France (FR) 2006-05-31 EP claimed
WO-2005016518-A1 HYDROTREATING AND/OR HYDROCRACKING CATALYST OF HYDROCARBONS AND PREPARATION THEREOF TOTAL FRANCE (FR) 2005-02-24 WO claimed
US-12501540-B2 Electronic device and manufacturing method thereof FUJIFILM CORPORATION (JP) 2025-12-16 US disclosed
CN-121011241-A Efficient serum metabolism fingerprint spectrum for diagnosis and prognosis of orbital lymphoma 上海交通大学 2025-11-25 CN disclosed
US-12451440-B2 Electronic device and manufacturing method thereof FUJIFILM CORPORATION (JP) 2025-10-21 US disclosed
WO-2000020414-A9 PIPERIDYLOXADIAZOLES AS DOPAMINE RECEPTOR ANTAGONISTS COMBICHEM INC (US) 2002-08-22 WO disclosed
US-6107313-A NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS COMBICHEM, INC. (US) 2000-08-22 US disclosed
WO-2000020414-A1 PIPERIDYLOXADIAZOLES AS DOPAMINE RECEPTOR ANTAGONISTS COMBICHEM, INC. (US) 2000-04-13 WO disclosed
US-4142044-A FLUORESCENT DYES HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11424006-B2 Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide PNMT, MAOA, HNMT L3MBTL1 3873/4885GAA 346/4885LMNA 2593/4885
US-20210128498-A1 TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE MAOA, PNMT, HNMT L3MBTL1 4566/4885GAA 179/4885LMNA 2828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.