Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 2/20 | 0.32 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5263488 | 1.00 | TSHR (0.37) | TSHRZDHHC20ATMHCAR2PTGES | |
| SCHEMBL1274716 | 0.98 | TSHR (0.36) | TSHRZDHHC20ATMHCAR2PTGES | |
| SCHEMBL1275404 | 0.94 | ZDHHC20 (0.40) | ZDHHC20HCAR2CES2HPGDALDH1A1 | |
| SCHEMBL1275704 | 0.92 | MEN1 (0.42) | TSHRZDHHC20HCAR2CES2HPGD | |
| SCHEMBL1274464 | 0.89 | HCAR2 (0.30) | HCAR2 | |
| SCHEMBL1275372 | 0.86 | ALDH1A1 (0.37) | TSHRALDH1A1APEX1 | |
| SCHEMBL1275293 | 0.85 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL1274486 | 0.85 | CES2 (0.41) | TSHRZDHHC20ATMHCAR2RARB | |
| SCHEMBL18486877 | 0.85 | ALDH1A1 (0.34) | TSHRALDH1A1 | |
| SCHEMBL147780 | 0.83 | CES1 (0.40) | TSHRCES2ALDH1A1APEX1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886507-B2 | MONOMERIC COMPOSITIONS EFFECTIVE AS WOUND CLOSURE DEVICES | ETHICON INC (US) | 2013-03-06 | — | — | EP | claimed |
| EP-0886507-B1 | MONOMERIC COMPOSITIONS EFFECTIVE AS WOUND CLOSURE DEVICES | CLOSURE MEDICAL CORP (US) | 2007-09-26 | — | — | EP | claimed |
| US-20180271505-A1 | Scaffolds for Joining Layers of Tissue at Discrete Points | ETHICON, INC. | 2018-09-27 | — | — | US | disclosed |