Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266197 | 0.92 | F10 (0.37) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4508547 | 0.85 | F10 (0.57) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5263799 | 0.82 | F10 (0.36) | F10CYP2C9 | |
| SCHEMBL5267728 | 0.80 | F10 (0.46) | F10F2 | |
| SCHEMBL5265451 | 0.78 | F10 (0.48) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5266654 | 0.78 | F10 (0.36) | F10PTGS2 | |
| SCHEMBL4512486 | 0.77 | F10 (0.47) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5314273 | 0.77 | F10 (0.42) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4507911 | 0.76 | F10 (0.53) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5265597 | 0.75 | F10 (0.48) | F10CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836198-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069946-A1 | SUBSTITUTED PYRROLIDINONES HAVING AN ANTITHROMBOTIC EFFECT, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-07-06 | — | — | WO | disclosed |