Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 8/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3289538 | 1.00 | KEAP1 (0.40) | KEAP1NFE2L2FFAR1MEN1KMT2A | |
| SCHEMBL3142767 | 0.92 | MEN1 (0.40) | FFAR1MEN1KMT2ALMNAPKM | |
| SCHEMBL3142761 | 0.92 | MEN1 (0.40) | FFAR1MEN1KMT2ALMNAPKM | |
| SCHEMBL5203422 | 0.92 | MEN1 (0.40) | FFAR1MEN1KMT2ALMNAPKM | |
| SCHEMBL3287419 | 0.90 | MEN1 (0.39) | KEAP1NFE2L2FFAR1MEN1KMT2A | |
| SCHEMBL5263054 | 0.90 | MEN1 (0.39) | KEAP1NFE2L2FFAR1MEN1KMT2A | |
| SCHEMBL5679194 | 0.88 | MEN1 (0.37) | FFAR1MEN1KMT2AALDH1A1APP | |
| SCHEMBL6552283 | 0.88 | MEN1 (0.37) | FFAR1MEN1KMT2AALDH1A1APP | |
| SCHEMBL5209967 | 0.87 | MEN1 (0.36) | FFAR1MEN1KMT2AAPPGHSR | |
| SCHEMBL3290077 | 0.87 | MEN1 (0.36) | FFAR1MEN1KMT2AAPPGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341753-B1 | CYCLOHEXYL(ALKYL)-PROPANOLAMINES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-09-26 | — | — | EP | disclosed |