Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 6/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920903 | 0.87 | PIK3CG (0.49) | TDP2PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3911294 | 0.84 | TDP2 (0.62) | TDP2PIK3CGPIK3CA | |
| SCHEMBL3920404 | 0.79 | PIK3CG (0.54) | TDP2PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3916311 | 0.78 | PIK3CG (0.53) | TDP2PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3920193 | 0.78 | PIK3CA (0.47) | TDP2PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3912369 | 0.76 | ROCK2 (0.44) | TDP2PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL1303772 | 0.71 | PIK3CG (0.43) | TDP2PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3913957 | 0.70 | ABL1 (0.49) | — | |
| SCHEMBL3378682 | 0.70 | PIK3CG (0.67) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL1302534 | 0.69 | PIK3CG (0.53) | TDP2PIK3CGPIK3CAPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799680-A2 | TRIAZOLOPYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006038116-A2 | TRIAZOLOPYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-04-13 | — | — | WO | disclosed |