Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 7/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.54 |
| ▸ | TDP2 | O95551 | 5/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | YES1 | P07947 | 1/20 | 0.42 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916311 | 0.88 | PIK3CG (0.53) | PIK3CGPIK3CATDP2JAK1AURKB | |
| SCHEMBL3920903 | 0.85 | PIK3CG (0.49) | PIK3CGPIK3CATDP2KDRPIK3CD | |
| SCHEMBL3920193 | 0.82 | PIK3CA (0.47) | PIK3CGPIK3CATDP2PIK3CDPIK3CB | |
| SCHEMBL3911294 | 0.80 | TDP2 (0.62) | PIK3CGPIK3CATDP2ABL1 | |
| SCHEMBL5264104 | 0.79 | TDP2 (0.51) | PIK3CGPIK3CATDP2PIK3CDPIK3CB | |
| SCHEMBL4074400 | 0.79 | MAPK1 (0.46) | AURKBMAPK1YES1HIPK1ABL1 | |
| SCHEMBL3912369 | 0.76 | ROCK2 (0.44) | PIK3CGPIK3CATDP2PIK3CDPIK3CB | |
| SCHEMBL31483064 | 0.71 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3921596 | 0.70 | JAK1 (0.36) | PIK3CGPIK3CAJAK1AURKBMAPK1 | |
| SCHEMBL4484215 | 0.69 | MAPK1 (0.44) | PIK3CAAURKBMAPK1YES1HIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524860-B2 | Antibacterial agents | PFIZER INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080021059-A1 | Antibacterial Agents | PFIZER INC. (US) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021059-A1 | Antibacterial Agents | CLPP, QDPR, CLSPN | PIK3CG 1002/4885PIK3CA 1931/4885TDP2 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.