Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | GALR3 | O60755 | 2/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.53 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5439670 | 0.82 | RAB9A (0.74) | NPC1RAB9AGALR3NR2F2AURKA | |
| SCHEMBL5264803 | 0.81 | NPC1 (0.57) | NPC1RAB9AGALR3NR2F2AURKA | |
| SCHEMBL5429336 | 0.81 | KDM4E (0.61) | NPC1RAB9AGALR3NR2F2AURKA | |
| SCHEMBL5436053 | 0.80 | NPC1 (0.55) | NPC1RAB9AGALR3NR2F2AURKA | |
| SCHEMBL5423720 | 0.80 | NPC1 (0.55) | NPC1RAB9AGALR3NR2F2AURKA | |
| SCHEMBL2187106 | 0.78 | EGFR (0.54) | — | |
| SCHEMBL7465161 | 0.76 | PDE5A (0.52) | PDE5AAURKARPS6KB1LMNAHTT | |
| SCHEMBL5423236 | 0.75 | RAB9A (0.73) | NPC1RAB9AGALR3NR2F2AURKA | |
| SCHEMBL27697469 | 0.74 | NPC1 (0.49) | NPC1RAB9AGALR3NR2F2AURKA | |
| SCHEMBL11414153 | 0.74 | EGFR (0.64) | RAB9AGALR3NR2F2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802632-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | Dow AgroSciences LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006047397-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2006-05-04 | — | — | WO | disclosed |