Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474668 | 0.90 | HTT (0.63) | PDE5AMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7467508 | 0.89 | MAPK1 (0.52) | PDE5AMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7475626 | 0.89 | HTT (0.52) | PDE5AMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7469664 | 0.89 | HTT (0.63) | PDE5AMAPK1MEN1KMT2AHTT | |
| SCHEMBL7464129 | 0.88 | MAPK1 (0.69) | PDE5AMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7469795 | 0.88 | EGFR (0.60) | PDE5AMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7474665 | 0.87 | HTT (0.62) | PDE5AMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7464363 | 0.87 | HTT (0.54) | PDE5AMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7474181 | 0.86 | MAPK1 (0.56) | MAPK1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL7528662 | 0.85 | EGFR (0.52) | PDE5AMAPK1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |