SCHEMBL526436

SCHEMBL526436

CCc1ccc(C(=O)Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.64
PLK1 P53350 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.50
TDP1 Q9NUW8 1/20 0.48
GAA P10253 3/20 0.47
LMNA P02545 2/20 0.47
NPC1 O15118 1/20 0.47
POLB P06746 1/20 0.47
AGTR1 P30556 1/20 0.47
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
MAPT P10636 3/20 0.46
RAB9A P51151 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CNR1 P21554 1/20 0.45
CNR2 P34972 1/20 0.45
HTT P42858 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7123177 0.94 ALDH1A1 (0.57) ALDH1A1PLK1SMN1; SMN2TDP1GAA
Chlorobenzene SCHEMBL27312024 0.87 ALDH1A1 (0.55) ALDH1A1PLK1SMN1; SMN2GAALMNA
Alcohol SCHEMBL29110704 0.82 ALDH1A1 (0.48) ALDH1A1PLK1SMN1; SMN2LMNAMAPT
SCHEMBL1019681 0.82 PLK1 (0.60) ALDH1A1PLK1TDP1GAALMNA
SCHEMBL2935942 0.80 ALDH1A1 (0.70) ALDH1A1PLK1SMN1; SMN2TDP1GAA
SCHEMBL1290930 0.80 KMT2A (0.58) ALDH1A1PLK1SMN1; SMN2LMNACYP2C9
SCHEMBL6259079 0.80 ALDH1A1 (0.70) ALDH1A1PLK1SMN1; SMN2TDP1TAS1R3
SCHEMBL7132233 0.80 HDAC1 (0.47) ALDH1A1PLK1GAAPOLBL3MBTL1
SCHEMBL20587670 0.79 ALDH1A1 (0.59) ALDH1A1LMNAMAPTHTTHPGD
SCHEMBL68148 0.79 ALDH1A1 (0.59) ALDH1A1LMNAMAPTHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 761 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060257-A Special polypropylene material for vehicle and preparation method thereof 潍坊川江塑胶制品有限公司 2026-05-19 CN claimed
WO-2024250573-A1 REVERSE OSMOSIS MEMBRANE PREPARATION METHOD AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY 沃顿科技股份有限公司 2024-12-12 WO claimed
CN-119098067-A Method for producing reverse osmosis membrane and reverse osmosis membrane produced thereby 沃顿科技股份有限公司 2024-12-10 CN claimed
CN-116333672-B UV (ultraviolet) binder suitable for camera module and preparation method thereof 广东德聚技术股份有限公司 2023-11-17 CN claimed
CN-116333672-A UV (ultraviolet) binder suitable for camera module and preparation method thereof 东莞市德聚胶接技术有限公司 2023-06-27 CN claimed
CN-114957250-B N- (9H-pyridine [2,3-b ] indol-4-yl) aryl carboxamide derivative and preparation method and application thereof 中国人民解放军北部战区总医院 2023-05-09 CN claimed
CN-114957250-A N- (9H-pyridine [2,3-b ] indole-4-yl) aryl formamide derivatives, and preparation method and application thereof 中国人民解放军北部战区总医院 2022-08-30 CN claimed
CN-114957156-A Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof 成都科宜高分子科技有限公司 2022-08-30 CN claimed
CN-114432900-A Preparation method of anti-pollution composite reverse osmosis membrane and anti-pollution composite reverse osmosis membrane prepared by same 沃顿科技股份有限公司 2022-05-06 CN claimed
CN-108929597-B Quantum dot conductive ink and quantum dot film 苏州星烁纳米科技有限公司 2021-10-22 CN claimed
CN-108929597-A Quantum dot conductive ink and quantum dot film 苏州星烁纳米科技有限公司 2018-12-04 CN claimed
CN-105777545-B A kind of preparation method of alpha-fluoro acrylic ester 衢州福瑞凯化工科技有限公司 2018-06-12 CN claimed
CN-105777545-A Preparation method of alpha-fluorinated acrylate 衢州福瑞凯化工科技有限公司 2016-07-20 CN claimed
CN-103232448-B One class contains 4-methyl isophthalic acid, 4,5-thiazoline carboxylic ester derivatives of 2,3-thiadiazoles and its production and use NANKAI UNIVERSITY (CN) 2016-03-30 CN claimed
CN-104710967-A Self-plugging releasing temperature resistant temporary plugging agent used for water-based drilling fluid and preparation method thereof CHINA PETROCHEMICAL CORP 2015-06-17 CN claimed
CN-104326934-A Preparation method of medical intermediate 2-chlorobenzene glycine methyl hydrochloride JIANFENG SHEN 2015-02-04 CN claimed
CN-104045652-A Preparation method of clopidogrel intermediate compound JIANFENG SHEN 2014-09-17 CN claimed
CN-103450500-A Novel organic ultraviolet light absorbent and preparation method thereof CAO JIANLIN 2013-12-18 CN claimed
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
EP-0639559-A1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM AND HAAS COMPANY (US) 1995-02-22 EP claimed