SCHEMBL1019681

SCHEMBL1019681

CCCc1ccc(C(=O)Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 2/20 0.60
THRB P10828 4/20 0.58
POLB P06746 3/20 0.58
CTDSP1 Q9GZU7 3/20 0.58
ALDH1A1 P00352 3/20 0.58
GAA P10253 2/20 0.58
KDM4E B2RXH2 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.56
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
KMT2A Q03164 2/20 0.51
MAPT P10636 1/20 0.51
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
THRA P10827 2/20 0.49
CNR2 P34972 1/20 0.47
RARB P10826 2/20 0.47
LPL P06858 1/20 0.47
LIPG Q9Y5X9 1/20 0.47
MCOLN3 Q8TDD5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7316586 0.94 RARB (0.56) PLK1THRBPOLBCTDSP1ALDH1A1
SCHEMBL8103655 0.92 RARB (0.59) PLK1THRBPOLBCTDSP1ALDH1A1
SCHEMBL6537301 0.89 THRB (0.53) PLK1THRBPOLBCTDSP1ALDH1A1
SCHEMBL6537300 0.89 THRB (0.53) PLK1THRBPOLBCTDSP1ALDH1A1
SCHEMBL1020423 0.88 RARB (0.62) PLK1THRBALDH1A1KMT2AMAPT
SCHEMBL7132233 0.86 HDAC1 (0.47) PLK1THRBPOLBCTDSP1ALDH1A1
SCHEMBL158152 0.86 THRA (0.67) THRBALDH1A1KMT2AMAPTTHRA
SCHEMBL2180222 0.84 THRA (0.70) THRBALDH1A1KMT2AMAPTTHRA
SCHEMBL8960387 0.84 THRA (0.70) THRBALDH1A1KMT2AMAPTTHRA
SCHEMBL1020543 0.84 THRA (0.70) THRBALDH1A1KMT2AMAPTTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024250573-A1 REVERSE OSMOSIS MEMBRANE PREPARATION METHOD AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY 沃顿科技股份有限公司 2024-12-12 WO claimed
CN-116410106-B Benzamide HBV capsid protein inhibitor and preparation method and application thereof 山东第二医科大学 2024-12-06 CN claimed
CN-116410106-A Benzamide HBV capsid protein inhibitor and preparation method and application thereof 潍坊医学院 2023-07-11 CN claimed
CN-114573721-A Quickly degradable biological plastic and preparation method thereof 今禾方吟科技(深圳)有限责任公司 2022-06-03 CN claimed
CN-114432900-A Preparation method of anti-pollution composite reverse osmosis membrane and anti-pollution composite reverse osmosis membrane prepared by same 沃顿科技股份有限公司 2022-05-06 CN claimed
EP-0399000-B1 LOW DIELECTRIC FLUORINATED POLY(PHENYLENE ETHER KETONE) FILM AND COATING US HEALTH (US) 1994-01-19 EP claimed
EP-0361416-A1 Polyamides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane HOECHST CELANESE CORPORATION (US) 1990-04-04 EP claimed
US-4914180-A Polyamides prepared from 2-(3-aminophenyl)-2-(4-aminophenyl) hexafluoro propane HOECHST CELANESE CORPORATION (US) 1990-04-03 US claimed
CN-120699015-B Pyridopyrimidine compound containing morpholine structure, and preparation method and application thereof 江西科技师范大学 2026-05-12 CN disclosed
WO-2024250573-A1 REVERSE OSMOSIS MEMBRANE PREPARATION METHOD AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY 沃顿科技股份有限公司 2024-12-12 WO disclosed
CN-116410106-B Benzamide HBV capsid protein inhibitor and preparation method and application thereof 山东第二医科大学 2024-12-06 CN disclosed
WO-2024235876-A1 PYRIDOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS FERNANDEZ CAPETILLO OSCAR (SE) 2024-11-21 WO disclosed
US-20240067597-A1 ESTER COMPOUND MITSUI CHEMICALS, INC. (JP) 2024-02-29 US disclosed
US-20230416517-A1 TRANSPARENT AND ANTIBACTERIAL ORGANIC GLASS AND MANUFACTURING METHOD THEREFOR Zhejiang Huashuaite New Material Technology Co., Ltd. (CN) 2023-12-28 US disclosed
US-4777282-A Preparation of monomers RAYCHEM LIMITED (GB) 1988-10-11 US disclosed
EP-0284256-A1 Benzodiazepine analogs MERCK & CO. INC. (US) 1988-09-28 EP disclosed
EP-0198865-A1 PREPARATION OF MONOMERS. RAYCHEM LTD (GB) 1986-10-29 EP disclosed
WO-1986002348-A1 PREPARATION OF MONOMERS RAYCHEM LIMITED (GB) 1986-04-24 WO disclosed
EP-0167919-A2 Benzodiazepine derivatives and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1986-01-15 EP disclosed
US-4001426-A HAVING CORONARY VASODILATOR ACTIVITY SMITHKLINE CORPORATION (US) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067597-A1 ESTER COMPOUND PPT1, GPER1, TCP1 PLK1 4778/4885THRB 1017/4885POLB 2326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.