Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5263339 | 0.88 | MAOA (0.47) | MAOAMAOBACHECNR2GPR55 | |
| SCHEMBL18584304 | 0.82 | MAOA (0.44) | MAOAMAOBACHECNR2GPR55 | |
| SCHEMBL17522757 | 0.77 | MAOA (0.45) | MAOAMAOBACHECNR2GPR55 | |
| SCHEMBL17501700 | 0.77 | MAOA (0.46) | MAOAMAOBACHECNR2GPR55 | |
| SCHEMBL4492747 | 0.73 | NOS1 (0.44) | MAOAMAOBACHEARNOS1 | |
| SCHEMBL4502778 | 0.70 | NOS1 (0.42) | MAOAMAOBACHEARNOS1 | |
| SCHEMBL6508140 | 0.70 | ESR1 (0.44) | MAOAMAOBACHEARNOS1 | |
| SCHEMBL6499021 | 0.70 | MAPT (0.43) | MAPTBRD4ALDH1A1LMNAGAA | |
| SCHEMBL15823883 | 0.69 | CYP1A2 (0.52) | MAOAMAOBGPR55IL4I1ALDH1A1 | |
| SCHEMBL6496075 | 0.68 | NOS1 (0.40) | MAOAMAOBACHEARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786807-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021340-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-03-02 | — | — | WO | disclosed |