Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.53 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19610302 | 0.82 | MAPT (0.48) | TEAD1TEAD3KMT2AMAPTALDH1A1 | |
| SCHEMBL19610377 | 0.80 | MAPT (0.45) | KMT2AMAPTALDH1A1 | |
| SCHEMBL3830625 | 0.80 | TEAD1 (0.73) | TEAD1TEAD3KMT2AALDH1A1LMNA | |
| SCHEMBL5208507 | 0.79 | TEAD1 (0.57) | TEAD1TEAD3KMT2AMAPTALDH1A1 | |
| SCHEMBL28064208 | 0.79 | TEAD1 (0.57) | TEAD1TEAD3KMT2AMAPTALDH1A1 | |
| SCHEMBL1532673 | 0.79 | FAAH (0.54) | NFE2L2TEAD1TEAD3KMT2ANAMPT | |
| SCHEMBL13806522 | 0.78 | NAMPT (0.46) | NFE2L2NAMPT | |
| SCHEMBL12509216 | 0.78 | NAMPT (0.56) | NAMPTALDH1A1 | |
| SCHEMBL28802165 | 0.77 | TEAD1 (0.55) | TEAD1TEAD3ALDH1A1 | |
| SCHEMBL23453708 | 0.77 | NFE2L2 (0.53) | NFE2L2TEAD1TEAD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849773-A1 | PYRIDYL NON-AROMATIC NITROGENATED HETEROCYCLIC-1-CARBOXYLATE ESTER DERIVATIVE | Astellas Pharma Inc. (JP) | 2007-10-31 | — | — | EP | claimed |