Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | HTR3A | P46098 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267035 | 0.90 | HTR3A (0.42) | GLAMEN1KMT2ATSHRRXFP1 | |
| SCHEMBL5386775 | 0.90 | HTR3A (0.42) | GLAMEN1KMT2ATSHRRXFP1 | |
| SCHEMBL2856069 | 0.82 | CHRNA7 (0.44) | GLANTMT1MEN1KMT2ATSHR | |
| SCHEMBL2856071 | 0.82 | CHRNA7 (0.44) | GLANTMT1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL4604601 | 0.79 | CHRNA7 (0.48) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL2854175 | 0.76 | GSK3B (0.52) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| SCHEMBL2851300 | 0.76 | CHRNA7 (0.47) | GLANTMT1MEN1KMT2ATSHR | |
| SCHEMBL2854049 | 0.76 | GSK3B (0.52) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| SCHEMBL2855680 | 0.76 | CHRNA7 (0.47) | GLANTMT1MEN1KMT2ATSHR | |
| SCHEMBL13528904 | 0.76 | GSK3B (0.52) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828179-A2 | NICOTINIC ALPHA-7 RECEPTOR LIGANDS AND PREPARATION AND USES THEREOF | Memory Pharmaceutical Corporation (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006069097-A2 | NICOTINIC ALPHA-7 RECEPTOR LIGANDS AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-06-29 | — | — | WO | disclosed |