Phthalic Acid

Phthalic Acid

SCHEMBL5265740

C=C(C)C(=O)OC.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
ALOX15 P16050 1/20 0.54
KDM4E B2RXH2 5/20 0.49
HSD17B10 Q99714 3/20 0.49
HPGD P15428 3/20 0.49
HMGB1 P09429 2/20 0.47
NAPRT Q6XQN6 2/20 0.47
ESR1 P03372 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
TSHR P16473 1/20 0.47
GGT1 P19440 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
BLM P54132 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
KMT2A Q03164 1/20 0.46
ELANE P08246 1/20 0.45
HTT P42858 1/20 0.44
CA12 O43570 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL8747582 0.86 TDP1 (0.44) ALDH1A1ALOX15KDM4EHSD17B10HPGD
SCHEMBL28094665 0.85 ALDH1A1 (0.46) ALDH1A1ALOX15KDM4EHSD17B10HPGD
Benzoic Acid SCHEMBL28159311 0.85 ALDH1A1 (0.58) ALDH1A1KDM4ENAPRTTSHRTDP1
Biphenyl SCHEMBL1395450 0.84 ALDH1A1 (0.62) ALDH1A1KDM4ETSHRELANESMN1; SMN2
Phthalic Acid SCHEMBL6322450 0.84 ALDH1A1 (0.64) ALDH1A1ALOX15KDM4EHSD17B10HPGD
Benzene SCHEMBL27313869 0.83 ALDH1A1 (0.83) ALDH1A1KDM4EHSD17B10TSHRTDP1
Benzene SCHEMBL28395547 0.83 ALDH1A1 (0.83) ALDH1A1KDM4EHSD17B10TSHRTDP1
Phthalic Acid SCHEMBL6916601 0.83 ALDH1A1 (0.52) ALDH1A1ALOX15KDM4EHSD17B10HPGD
Phenol SCHEMBL27515547 0.82 ALDH1A1 (0.60) ALDH1A1KDM4EHSD17B10NAPRTESR1
Phenol SCHEMBL2145525 0.82 ALDH1A1 (0.60) ALDH1A1KDM4EHSD17B10NAPRTESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106752865-B A kind of cured PVC coating of UV-LED light source and preparation method thereof 天津久日新材料股份有限公司 2019-06-14 CN disclosed
CN-109187118-A Hard tissue pathological section unfolding method and device 中南大学湘雅医院 2019-01-11 CN disclosed
US-20070148124-A1 Cellulose and acrylic based polymers and the use thereof for the treatment of infectious diseases NOVAFLUX INC. 2007-06-28 US disclosed
EP-1749041-A2 CELLULOSE AND ACRYLIC BASED POLYMERS AND THE USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES Nova Flux Biosciences, Inc. (US) 2007-02-07 EP disclosed
WO-2005111112-A2 CELLULOSE AND ACRYLIC BASED POLYMERS AND THE USE THEREOF FOR THE TREATMENT OF INFECTIOUS DISEASES NOVA FLUX BIOSCIENCES, INC. (US) 2005-11-24 WO disclosed
US-20050244365-A1 Methods, compositions, formulations, and uses of cellulose and acrylic-based polymers NOVAFLUX BIOSCIENCES, INC. (US) 2005-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050244365-A1 Methods, compositions, formulations, and uses of cellulose and acrylic-based polymers DNA2, DNASE1, SMC2 ALDH1A1 2507/4885ALOX15 4583/4885KDM4E 3724/4885
US-20070148124-A1 Cellulose and acrylic based polymers and the use thereof for the treatment of infectious diseases ALG1, CHIT1, CHIA ALDH1A1 3346/4885ALOX15 2638/4885KDM4E 1151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.