Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL135536 | 0.86 | GSK3B (0.48) | NAPRTBCHEPTGS2GSK3AGSK3B | |
| SCHEMBL31375408 | 0.79 | ALDH1A1 (0.42) | GSK3AGSK3BALDH1A1ALOX15LMNA | |
| SCHEMBL7782551 | 0.76 | NAPRT (0.42) | NAPRTBCHEPTGS2GSK3AGSK3B | |
| SCHEMBL14275262 | 0.76 | NAPRT (0.62) | NAPRTBCHEPTGS2GSK3AGSK3B | |
| SCHEMBL18865781 | 0.75 | USP1 (0.36) | KDM4ESMN1; SMN2MAPT | |
| SCHEMBL18865479 | 0.75 | ELANE (0.42) | ALDH1A1KDM4EKMT2AMAPTFPR2 | |
| SCHEMBL27726094 | 0.71 | KMT2A (0.40) | NAPRTBCHEPTGS2GSK3AGSK3B | |
| SCHEMBL8127154 | 0.70 | GSK3A (0.54) | NAPRTBCHEPTGS2GSK3AGSK3B | |
| SCHEMBL2227677 | 0.70 | P2RX4 (0.41) | NAPRTBCHEALDH1A1ALOX15LMNA | |
| SCHEMBL28561415 | 0.70 | GSK3A (0.48) | NAPRTBCHEPTGS2GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257908-A1 | MODIFIED DNA-ENCODED CHEMICAL LIBRARY AND METHODS RELATED THERETO | TECHNISCHE UNIVERSITAET DORTMUND (DE) | 2023-08-17 | — | — | US | disclosed |
| EP-4127162-A1 | MODIFIED DNA-ENCODED CHEMICAL LIBRARY AND METHODS RELATED THERETO | Technische Universität Dortmund (DE) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021191333-A1 | MODIFIED DNA-ENCODED CHEMICAL LIBRARY AND METHODS RELATED THERETO | TECHNISCHE UNIVERSITÄT DORTMUND (DE) | 2021-09-30 | — | — | WO | disclosed |
| EP-1833800-A1 | PYRAZOLONE COMPOUNDS AS METABOTROPIC GLUTAMATE RECEPTOR AGONISTS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | AstraZeneca AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006071730-A1 | PYRAZOLONE COMPOUNDS AS METABOTROPIC GLUTAMATE RECEPTOR AGONISTS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | ASTRAZENECA AB (SE) | 2006-07-06 | — | — | WO | disclosed |
| US-5854379-A | Thermal decomposition degreasing method and molded products thereof | KABUSHIKI KAISHA KOMATSU SEISAKUSHO (JP) | 1998-12-29 | — | — | US | disclosed |
| EP-0801082-A2 | Resin for solid-phase peptide synthesis and methods of making it | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1997-10-15 | — | — | EP | disclosed |
| US-5545698-A | Polyethylene glycol derivatives for solid-phase applications | UNIVERSITY OF MINNESOTA (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0546055-B1 | POLYETHYLENE GLYCOL DERIVATIVES FOR SOLID-PHASE APPLICATIONS | UNIV MINNESOTA (US) | 1996-07-10 | — | — | EP | disclosed |
| EP-0687691-A2 | Resin for solid-phase peptide synthesis and methods of making it | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-12-20 | — | — | EP | disclosed |
| US-5306562-A | Xanthenylamide handle for use in peptide synthesis | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-04-26 | — | — | US | disclosed |
| US-5235028-A | Polyethylene glycol derivatives for solid-phase applications | UNIVERSITY OF MINNESOTA (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0546055-A1 | POLYETHYLENE GLYCOL DERIVATIVES FOR SOLID-PHASE APPLICATIONS. | UNIV MINNESOTA (US) | 1993-06-16 | — | — | EP | disclosed |
| US-5117009-A | XANTHENYLAMIDE HANDLE FOR USE IN PEPTIDE SYNTHESIS | UNIVERSITY OF MINNESOTA (US) | 1992-05-26 | — | — | US | disclosed |
| WO-1992004384-A1 | POLYETHYLENE GLYCOL DERIVATIVES FOR SOLID-PHASE APPLICATIONS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1992-03-19 | — | — | WO | disclosed |
| EP-0473411-A1 | Xanthenylamide handle for use in peptide synthesis and methods of producing said handle and support incorporating it | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1992-03-04 | — | — | EP | disclosed |
| US-4537886-A | β-lactam antibacterial agents and compositions containing them | BEECHAM GROUP P.L.C. (GB) | 1985-08-27 | — | — | US | disclosed |
| EP-0090656-A1 | Penicillins, a process for the preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1983-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257908-A1 | MODIFIED DNA-ENCODED CHEMICAL LIBRARY AND METHODS RELATED THERETO | DUT, DCTD, DNMT1 | NAPRT 209/4885BCHE 1745/4885PTGS2 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.