Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.45 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13533082 | 0.83 | ADRB1 (0.56) | DRD2DRD3HTR2ADRD1HTR1A | |
| SCHEMBL13741102 | 0.73 | DRD2 (0.43) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL8531362 | 0.72 | CREBBP (0.40) | ADRA2CHTR2C | |
| SCHEMBL6863375 | 0.72 | DRD2 (0.80) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL5356729 | 0.72 | GAA (0.51) | DRD2DRD3DRD4ADRA2CHTR1A | |
| SCHEMBL24605901 | 0.71 | DRD2 (0.54) | DRD2DRD3HTR2AHTR1AMAPK1 | |
| SCHEMBL13499602 | 0.71 | ADRB1 (0.67) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL9049827 | 0.71 | DRD2 (0.54) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL31051847 | 0.71 | ADRB1 (0.67) | DRD2DRD3DRD4HTR2ADRD1 | |
| SCHEMBL15311895 | 0.70 | DRD2 (0.46) | DRD2DRD3DRD4HTR2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742632-A2 | TRANSDERMAL IONTOPHORETIC DELIVERY OF PIPERAZINYL-2(3H)-BENZOXAZOLONE COMPOUNDS | Solvay Pharmaceuticals B.V. (NL) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005107754-A2 | TRANSDERMAL IONTOPHORETIC DELIVERY OF PIPERAZINYL-2(3H)-BENZOXAZOLONE COMPOUNDS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2005-11-17 | — | — | WO | disclosed |