Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264931 | 0.85 | CYP4F2 (0.54) | ALDH1A1PARP1 | |
| SCHEMBL28284087 | 0.85 | PARP14 (0.51) | PARP14MAOBOPRK1OPRM1OPRD1 | |
| SCHEMBL15310414 | 0.84 | PARP14 (0.60) | PARP14MAOBOPRK1OPRM1OPRD1 | |
| SCHEMBL1532900 | 0.82 | KDM4E (0.54) | PARP14MAOB | |
| SCHEMBL27702480 | 0.81 | HRH3 (0.48) | PARP14MAOBKCNH2ACHE | |
| SCHEMBL12736064 | 0.79 | ROCK2 (0.47) | PARP14MAOBOPRK1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL1532855 | 0.78 | ROCK2 (0.47) | PARP14MAOBOPRK1OPRM1OPRD1 | |
| SCHEMBL23022734 | 0.76 | CARM1 (0.57) | MAOBMAOA | |
| SCHEMBL1532748 | 0.73 | FAAH (0.54) | PARP14MAOBOPRK1OPRM1KCNH2 | |
| SCHEMBL12509044 | 0.72 | PARP14 (0.55) | PARP14LMNATNKSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607362-A1 | Piperidine and piperazine carboxylates as FAAH inhibitors | Astellas Pharma Inc. (JP) | 2013-06-26 | — | — | EP | disclosed |
| EP-1849773-A1 | PYRIDYL NON-AROMATIC NITROGENATED HETEROCYCLIC-1-CARBOXYLATE ESTER DERIVATIVE | Astellas Pharma Inc. (JP) | 2007-10-31 | — | — | EP | disclosed |