Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 6/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | DRD4 | P21917 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190924 | 0.86 | PRCP (0.48) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL18686402 | 0.72 | DRD1 (0.35) | MAPTALDH1A1TP53CYP2D6HSD17B10 | |
| SCHEMBL10773340 | 0.69 | SLC6A2 (0.36) | PTPRAMAPTALDH1A1HPGDGLA | |
| SCHEMBL627814 | 0.67 | CYP2D6 (0.39) | MAPTALDH1A1TP53CYP2D6HSD17B10 | |
| SCHEMBL940897 | 0.65 | F2R (0.31) | — | |
| SCHEMBL5972310 | 0.64 | ALDH1A1 (0.32) | MAPTALDH1A1HPGDCYP1A2GLA | |
| SCHEMBL1471223 | 0.64 | DRD1 (0.37) | MAPTALDH1A1TP53CYP2D6HSD17B10 | |
| SCHEMBL6985456 | 0.63 | PRCP (0.66) | CYP2D6CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4513395 | 0.63 | RAB9A (0.36) | MAPTALDH1A1TP53HSD17B10KDM4E | |
| SCHEMBL627815 | 0.62 | PRCP (0.49) | MAPTCYP2D6KDM4ECYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841766-A1 | PYRROLOPYRIDINES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | claimed |
| WO-2006077401-A1 | PYRROLOPYRIDINES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | claimed |